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Orderly recruitment of thermoeffectors in resting humans

机译:有序招募在休息人类的热质福利

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The recruitment of thermoeffectors, including thermoregulatory behavior, relative to changes in body temperature has not been quantified in humans. We tested the hypothesis that changes in skin blood How, behavior, and sweating or metabolic rate are initiated with increasing changes in mean skin temperature (T_(skin)) in resting humans. While wearing a water-perfused suit, 12 healthy young adults underwent heat (Heat) and cold stress (Cold) that induced gradual changes in T_(skin). Subjects controlled the temperature of their dorsal neck to their perceived thermal comfort. Thus neck skin temperature provided an index of thermoregulatory behavior. Neck skin temperature (T_(skin)), core temperature (T_(core)), metabolic rate, sweat rate, and nonglabrous skin blood flow were measured continually. Data were analyzed using segmental regression analysis, providing an index of thermoeffector activation relative to changes in T_(skin). In Heat, increases in skin blood flow were observed with the smallest elevations in T_(skin) (P < 0.01). Thermal behavior was initiated with an increase in T_(skin) of 2.4 ± 1.3°C (mean ± SD, P = 0.04), while sweating was observed with further elevations in T_(skin) (3.4 ± 0.5°C, P = 0.04), which coincided with increases in T_(skin) (P = 0.98). In Cold, reductions in skin blood flow occurred with the smallest decrease in T_(skin) (P < 0.01). Thermal behavior was initiated with a T_(skin) decrease of 1.5 ± 1.3°C, while metabolic rale (P = 0.10) and T_(core) (P = 0.76) did not change throughout. These data indicate that autonomic and behavioral thermoeffectors are recruited in coordination with one another and likely in an orderly manner relative to the comparative physiological cost.
机译:在人类中,相对于体温变化的热调节行为的招募是植物的招募。我们测试了如何在休息人类中的平均皮肤温度(T_(皮肤))的变化时,开始如何发生皮肤血液变化的假设。在穿着水灌注的西装时,12个健康的年轻成年人接受了热量(热)和冷应激(冷)诱导T_(皮肤)的逐渐变化。受试者将背颈的温度控制在其感知的热舒适度。因此,颈部皮肤温度提供了热调节行为的指标。颈部皮肤温度(T_(皮肤)),核心温度(T_(核心)),代谢率,汗水率和不断的性能血流。使用分段回归分析分析数据,提供了相对于T_(皮肤)的变化的热映射器激活指数。在热量中,观察到皮肤血流的增加,在T_(皮肤)中最小的凸起(P <0.01)。在2.4±1.3°C的T_(皮肤)的增加(平均±SD,P = 0.04)的增加,在T_(皮肤)进一步升高(3.4±0.5°C,P = 0.04 ),恰逢T_(皮肤)的增加(P = 0.98)。在寒冷中,T_(皮肤)的最小降低发生皮肤血流的减少(P <0.01)。用T_(皮肤)降低为1.5±1.3°C的热行为,而代谢rale(p = 0.10)和T_(核心)(p = 0.76)在整个过程中没有变化。这些数据表明,自主主义和行为热量缺散剂在彼此的协调中招募,并且可能相对于比较生理成本的有序方式。

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