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首页> 外文期刊>Applied Microbiology and Biotechnology >Biological synthesis of metallic nanoparticles (MNPs) by plants and microbes: their cellular uptake, biocompatibility, and biomedical applications
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Biological synthesis of metallic nanoparticles (MNPs) by plants and microbes: their cellular uptake, biocompatibility, and biomedical applications

机译:植物和微生物的金属纳米颗粒(MNP)的生物合成:它们的细胞吸收,生物相容性和生物医学应用

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摘要

Metallic nanoparticles (MNPs) with their diverse physical and chemical properties have been applied in various biomedical domains. The increasing demand for MNPs has attracted researchers to develop straightforward, inexpensive, simple, and eco-friendly processes for the enhanced production of MNPs. To discover new biomedical applications first requires knowledge of the interactions of MNPs with target cells. This review focuses on plant and microbial synthesis of biological MNPs, their cellular uptake, biocompatibility, any biological consequences such as cytotoxicity, and biomedical applications. We highlighted the involvement of biomolecules in capping and stabilization of MNPs and the effect of physicochemical parameters particularly the pH on the synthesis of MNPs. Recently achieved milestones to understand the role of synthetic biology (SynBiol) in the synthesis of tailored MNPs are also discussed.
机译:在各种生物医学结构域中施加了金属纳米颗粒(MNP),其具有各种物理和化学性质。 越来越多的MNPS的需求吸引了研究人员,为增强MNP的生产而开发直接,廉价,简单,环保的过程。 为了发现新的生物医学应用,首先需要了解MNP与靶细胞的相互作用。 本综述侧重于植物和微生物合成生物MNP,它们的细胞吸收,生物相容性,任何生物后果,如细胞毒性,以及生物医学应用。 我们强调了生物分子参与MNP的封顶和稳定性以及物理化学参数的影响,特别是MNPS合成的pH值。 最近讨论了达到了了解合成生物学(Sysbiol)在量定制的MNP的合成中的里程碑。

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