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首页> 外文期刊>Applied radiation and isotopes: including data, instrumentation and methods for use in agriculture, industry and medicine >Performance comparison of two Olympus InnovX handheld x-ray analyzers for feasibility of measuring arsenic in skin in vivo - Alpha and Delta models
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Performance comparison of two Olympus InnovX handheld x-ray analyzers for feasibility of measuring arsenic in skin in vivo - Alpha and Delta models

机译：两种Olympus Innovex手持X射线分析仪的性能比较，以便在体内砷测量砷的可行性 - Alpha和Delta模型

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摘要

The Figure-Of-Merit (FOM) performance, a combination of detection limit and dose, is compared between two generations of handheld X-Ray Fluorescence (XRF) spectrometers for the feasibility of in vivo XRF measurement of arsenic (As) in skin. The Olympus InnovX Delta model analyzer (40 kVp using either 37 or 17 mu A) was found to show improvements in Minimum Detection Limit (MDL) using arsenic As-doped skin calibration phantoms with bulk tissue backing, when compared to the first generation InnovX Alpha model (40 kVp, 20 mu A) in 120 s measurements. Differences between two different definitions of MDL are discussed. On the Delta system, an MDL of (0.462 +/- 0.002) mu g/g As was found in phantoms, with a nylon backing behind to mimic bulk tissue behind skin. The equivalent and effective doses were found to be (10 +/- 2) mSv and similar to 7 x 10(-3) mu Sv respectively for the Alpha and (15 +/- 4) mSv and similar to 8 x 10(-3) mu Sv respectively for the Delta system in 120 s exposures. Combining MDL and effective dose, a lower (better) FOM was found for the Delta, (1.7 +/- 0.4) ppm mSv(1/2), compared to (4.4 +/- 0.5) ppm mSv(1/2) for the Alpha model system. The Delta analyzer demonstrates improved overall system performance for a rapid 2-min measurement in As skin phantoms, such that it can be considered for use in populations exposed to arsenic.
机译：在两代手持式X射线荧光（XRF）光谱仪之间比较了优异（FOM）性能，检测极限和剂量的组合，用于在皮肤上的砷（AS）中的体内XRF测量的可行性。奥林巴斯Innovx Delta模型分析仪（使用37或17 mu a）的型号（使用37或17 mu a）显示，与第一代Innovex alpha相比，使用砷的含有掺杂皮肤校准模型显示最小检测限（MDL）的改进。 120 S测量中的模型（40 kVp，20 mu a）。讨论了两个不同的MDL定义之间的差异。在Delta系统上，MDL（0.462 +/- 0.002）mu g / g，如幻像中发现，用尼龙背靠背衬垫，以模仿皮肤后面的散装组织。发现等效和有效的剂量是（10 +/- 2）MSV，分别为α和（15 +/- 4）MSV和（15 +/- 4）和类似于8×10（ - 3）MU SV分别用于120秒曝光中的DELTA系统。与（4.4 +/- 0.5）PPM MSV（1/2）相比，组合MDL和有效剂量，较低（1.7 +/- 0.4）PPM MSV（1/2），（1.7 +/- 0.4）ppm msv（1/2） alpha模型系统。 Delta Analyzer在作为皮肤幻影中的快速2分钟测量的情况下，可以改善整体系统性能，使得可以考虑在暴露于砷的群体中使用。

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