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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Adequate Margins to Prevent Local Re-recurrence of Rectal Cancer: Viewpoint of Pathological Findings
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Adequate Margins to Prevent Local Re-recurrence of Rectal Cancer: Viewpoint of Pathological Findings

机译：足够的边缘以防止直肠癌的局部重新复发：病理发现的观点

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Background: A sufficient surgical margin is critical for preventing re-recurrence and achieving R0 status after resection of a local recurrence of rectal cancer (LRRC). Patients and Methods: Re-recurrence-free survival was analyzed in 110 cases of LRRC according to histological type of primary lesion. The circumferential resection margin (CRM) was classified as 'R1' (x=0 mu m), 'R0 shortness' (0 mu m = 2,000 mu m). The histological change from the primary lesion to the recurrent lesion was classified as 'No change pattern', from well-to moderately-differentiated (W/M) to an expanding lesion; as 'Change pattern', from W/M to an infiltrating lesion. Results: Re-recurrence-free survival was better in 'R0 longness' than 'R0 shortness' groups and showed that 'No change pattern' cases had considerably better prognosis than 'Change pattern' cases. Conclusion: Ensuring a CRM >2,000 mu m during resection of LRRC is more likely to prevent rerecurrence. Cases with poorly differentiated carcinoma from the primary lesion to the recurrent lesion tend to have poor prognoses.
机译：背景：足够的手术边缘对于在切除直肠癌（LRRC）的局部复发后，对预防重新发生和实现R0状态至关重要。患者及方法：根据原发性病变组织学类型分析110例LRRC的再复制存活。周向切除余量（CRM）被归类为“R1”（x = 0 mu m），'r0短积'（0 mu m = 2,000 mu m） 。从初级病变到复发性病变的组织学变化被归类为“没有变化模式”，从良好地分化（W / M）到扩张的病变;作为“改变模式”，从w / m到渗透病变。结果：重新发生的存活率比“R0长度”群体更好，而不是“R0短暂”群体，并显示“没有变化模式”病例比“改变模式”案件更好地预测。结论：在切除LRRC期间确保CRM> 2,000 mu m更有可能预防rereCurrence。从初级病变到复发性病变的癌不同癌的病例往往具有差的预测。

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