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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >A Giant Gastric Gastrointestinal Stromal Tumor Successfully Resected Following Neoadjuvant Treatment With Imatinib Mesylate
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A Giant Gastric Gastrointestinal Stromal Tumor Successfully Resected Following Neoadjuvant Treatment With Imatinib Mesylate

机译：在Neoadjuvant治疗后，巨型胃胃肠道肿瘤肿瘤成功切除，用伊马替尼甲壳酸伊替尼酸盐治疗

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Background: Neoadjuvant treatment with imatinib mesylate (IM) has not been established for gastrointestinal stromal tumor (GIST). A case of a giant gastric GIST that was radically resected following neoadjuvant therapy with IM is reported. Case Report: A 71-year-old woman with abdominal distension was referred to our hospital for treatment. Contrast-enhanced computed tomography showed a large (>30 cm), heterogeneous mass, with dilated vessels around the tumor. The diagnosis was a gastric GIST by endoscopic ultrasound-fine needle aspiration, and neoadjuvant therapy with 400 mg IM daily was started. Radical surgery was performed after 13 months. Since the tumor was not invasive, complete resection by partial gastrectomy was achieved without the need for combined resection of other organs. The patient remains alive without recurrence 12 months after surgery. Conclusion: A giant GIST, larger than 30 cm in size, is quite rare. Neoadjuvant IM treatment should be considered in the management of large GISTs.
机译：背景：尚未建立用伊马替尼甲磺酸盐（IM）的Neoadjuvant治疗，用于胃肠道基质肿瘤（GIST）。报道了IM内辅助治疗后术后切除的巨型胃部的情况。案例报告：一名患有腹胀的71岁女性被提交给我们医院进行治疗。对比度增强的计算断层摄影显示出大（> 30cm），异质质量，肿瘤周围的扩张血管。诊断是通过内窥镜超声细小针的吸入胃部，并开始每天400毫克的Neoadjuvant治疗。 13个月后进行自由基手术。由于肿瘤不侵入性，因此通过部分胃切除术进行完全切除，而无需组合切除其他器官。患者在手术后12个月内仍然活着。结论：大于30厘米的巨大;尺寸大于30厘米，非常罕见。在大型名人的管理中应考虑Neoadjuvant IM治疗。

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