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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Diagnosis of Malignant Pleural Effusion Using CT Scan and Pleural-Fluid Cytology Together. A Preliminary Case-Control Study
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Diagnosis of Malignant Pleural Effusion Using CT Scan and Pleural-Fluid Cytology Together. A Preliminary Case-Control Study

机译：用CT扫描和胸腔流体细胞学诊断恶性胸腔积液。 初步案例对照研究

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Background/Aim: The purposes of this study were to evaluate the usefulness of chest computed tomographic (CT) scan plus pleural fluid cytology (PFC) together in patients with malignant pleural effusion (PE), and to compare the results of these diagnostic tools in patients with malignant PE due to non-small-cell lung cancer and pulmonary metastases from other malignancies. Patients and Methods: The medical records of 185 patients with PE, who underwent chest CT, PFC and video-assisted thoracoscopy (VATS) thoracentesis followed by VATS-guided biopsy for diagnostic purpose, were reviewed. At the final diagnosis, 123 (66.5%) patients had malignant PE (cases), and 62 (33.5%) had benign PE (controls). Results: Overall, the sensitivity, specificity, and accuracy of CT and PFC were 65.0% vs. 67.5% 98.4% vs. 98.4%, and 76.2% vs. 77.8%, respectively. The combination of CT plus PFC significantly improved sensitivity (86.2%, p=0.003) and accuracy (90.8%, p=0.02). Conclusion: CT and PFC used together may lead to approximately 100% specificity and >90% sensitivity in distinguishing between benign and malignant PE.
机译：背景/目的：本研究的目的是评估恶性胸腔积液（PE）患者中胸部计算断层扫描（CT）扫描加胸腔液体细胞学（PFC）的用量，并比较这些诊断工具的结果恶性体育病患者由于非小细胞肺癌和来自其他恶性肿瘤的肺转移。患者及方法：综述了185例PE患者的医疗记录，胸部CT，PFC和视频辅助胸腔镜（VATS）胸腔胸腔（VATS）胸腔胸腔划分，进行了诊断目的的大桶引导活检。在最终诊断中，123名（66.5％）患者患有恶性PE（病例），62例（33.5％）具有良性体育（对照）。结果：总体而言，CT和PFC的敏感性，特异性和准确性分别为65.0％，分别为65.0％98.4％，分别为98.4％，76.2％与77.8％。 CT加上PFC的组合显着提高了灵敏度（86.2％，P = 0.003）和精度（90.8％，P = 0.02）。结论：CT和PFC一起使用的CT和PFC可能导致良性和恶性PE之间的敏感性大约100％，敏感度> 90％。

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