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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >The Short- and Long-term Outcomes of Esophagectomy for Esophageal Cancer in Patients Older than 75 Years
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The Short- and Long-term Outcomes of Esophagectomy for Esophageal Cancer in Patients Older than 75 Years

机译:75岁患者食管癌食管癌的短期和长期结果

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Background: The short- and long- term outcomes of esophagectomy for esophageal cancer were fully evaluated in patients older than 75 years of age. Patients and Methods: The present study selected patients who received esophagectomy for esophageal cancer. Patients were divided into non-elderly patients [age = 75 years (elderly group)]. The postoperative surgical morbidity, postoperative 30-days mortality, recurrence-free survival (RFS), and overall survival (OS) rates were evaluated between the non-elderly group and elderly group. Results: One hundred twenty-two patients were evaluated in this study. Ninety-eight patients and 24 patients were classified into the non-elderly group and elderly group, respectively. The postoperative surgical complication rates in the non-elderly and elderly groups were 71.4% and 75.0%. There was not a statistically significant difference between the two groups (p = 0.710). Mortality was observed in 1 patient in the elderly group (4.2%) due to cardiovascular disease. Significant differences were observed in the five-year OS and RFS rates of the elderly and non-elderly groups (55.4% vs. 29.7%, p = 0.0017 and 42.2% vs. 21.2%, p = 0.0334, respectively). Conclusion: Although the rate of postoperative surgical complications after esophagectomy for esophageal cancer was almost equal in the elderly and the non-elderly patients, significant differences were observed in the mortality and long-term outcomes of the two groups. Thus, the surgical strategy and perioperative care must be carefully planned for esophageal cancer patients older than 75 years of age.
机译:背景:对食管癌食管癌的短期和长期结果完全评估了75岁的患者。患者及方法:本研究选择接受食管癌食管切除术的患者。患者分为非老年患者[年龄= 75岁(老年人)]。术后手术发病率,术后30天死亡率,无复发存活率(RFS)和总存活(OS)率进行了评估,在非老年团和老年人之间评价。结果:本研究评估了一百二十二名患者。九十八名患者和24名患者分别分为非老年群体和老年人。非老年人和老年群体的术后外科并发症率为71.4%和75.0%。两组之间没有统计学显着差异(P = 0.710)。由于心血管疾病,1例患者在1例患者中观察到死亡率。在五年的OS和老年人和非老年人的RFS速率下观察到显着差异(55.4%与29.7%,P = 0.0017和42.2%,分别为21.2%,P = 0.0334)。结论:虽然食管癌食管切除术后的术后手术并发症率几乎相等,但非老年患者几乎相等,但在两组的死亡率和长期成果中观察到显着差异。因此,必须仔细计划手术策略和围手术期护理,用于75岁的食管癌患者。

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