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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Impact of Anastomotic Leakage on Overall and Disease-free Survival After Surgery for Gastric Carcinoma: A Systematic Review
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Impact of Anastomotic Leakage on Overall and Disease-free Survival After Surgery for Gastric Carcinoma: A Systematic Review

机译:吻合渗漏对胃癌外科术后整体和无病生存的影响:系统评价

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Background/Aim: Gastric cancer is the fifth most frequently diagnosed cancer and the second most common cause of cancer-related death. The only potentially curative treatment is surgical resection, which is associated with potentially severe complications, such as anastomotic leakage. The aim of this systematic review was to evaluate the relationship between anastomotic leakage and overall and disease-free survival after surgery for gastric cancer. Materials and Methods: A systematic literature search was performed and 7 articles published between 2010 and 2019 were included, including a total of 7,167 patients. Results: Among the included studies the frequency of anastomotic leakage ranged from 6 to 41%. Patients affected by anastomotic leakage had an overall survival ranging between 4.1 and 97.6 months, whereas patients who did not experience anastomotic leakage had an overall survival between 23 and 109.5 months. Conclusion: Closer follow-up or even more aggressive oncological therapy may be considered for patients affected by anastomotic leakage after surgery for gastric cancer.
机译:背景/目的:胃癌是最常见的癌症和癌症相关死亡的第二个最常见的原因。唯一潜在的治疗方法是手术切除,其与潜在严重的并发症相关,例如吻合泄漏。这种系统审查的目的是评估胃癌手术后吻合渗漏和无病生存之间的关系。材料和方法:进行系统文献搜索,并在2010年至2019年间公布了7篇文章,其中共有7,167名患者。结果:在内的研究中,吻合渗漏的频率范围为6%至41%。受吻合口渗漏影响的患者在4.1%和97.6个月之间的整体存活率在4.1和97.6个月之间,而没有经历吻合渗漏的患者在23%至109.5个月之间存在整体生存率。结论:对于受胃癌手术后吻合口渗漏影响的患者,可以考虑更接近的后续随访或更具侵略性的肿瘤治疗。

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