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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >A Pre-operative Score to Discriminate Fibroepithelial Lesions of the Breast: Phyllode Tumor or Fibroadenoma?
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A Pre-operative Score to Discriminate Fibroepithelial Lesions of the Breast: Phyllode Tumor or Fibroadenoma?

机译：术前分数鉴别乳房的纤维素病变：Phyllode肿瘤或纤维腺瘤？

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Background/Aim: Fibroepithelial lesions (FEL) of the breast include fibroadenomas and phyllodes tumors (PT). Their histologic characteristics on core needle biopsy can overlap, while their clinical management is different. The aim of this study was to develop and to validate a pre-operative score for the diagnosis of PT with surgical decision rules. Patients and Methods: We developed a pre-operative score for the diagnosis of PT by performing logistic regression on 217 FEL of the Rene Huguenin Hospital. This score and the surgical decision rules were validated on 87 FEL of the Lariboisiere Hospital. Results: Three variables were independently and significantly associated with PT: age >= 40 years, mammography's tumor size >= 3 cm and PT diagnosed by CNB. The pre-operative score was based on these three criteria with values ranging from 0 to 10. Surgical decision rules were created: the low-risk group of PT (score 7) had a specificity of 93.5% and a LR+ of 4.4. In the validation sample, surgical decision rules were applied. Conclusion: These surgical decision rules may prove useful in deciding which FEL needs surgical resection.
机译：背景/目的：乳房的纤维素病变（FEL）包括纤维腺瘤和植物肿瘤（PT）。它们在核心针活检的组织学特征可以重叠，而他们的临床管理是不同的。本研究的目的是发展，并验证诊断PT与外科决策规则的绩效评分。患者和方法：通过在Rene Huguenin医院的217个Fel上表演Logistic回归，开发了PT的诊断前的绩效评分。该得分和手术决策规则在Lariboisiere医院的87份菲尔核查。结果：三个变量独立且与PT相关，令人职业_ = 40年，乳房X线摄影的肿瘤大小> = 3厘米，PT由CNB诊断。术前分数基于这三个标准，其中值0到10.外科决策规则是创建的：PT（得分7）的低风险组的特异性为93.5％和4.4的LR +。在验证样本中，应用手术决策规则。结论：这些手术决策规则可证明在确定外科切除的母细胞需要。

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