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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Comparison of Dose Distributions When Using Carbon Ion Radiotherapy Versus Intensity-modulated Radiotherapy for Hepatocellular Carcinoma With Macroscopic Vascular Invasion: A Retrospective Analysis
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Comparison of Dose Distributions When Using Carbon Ion Radiotherapy Versus Intensity-modulated Radiotherapy for Hepatocellular Carcinoma With Macroscopic Vascular Invasion: A Retrospective Analysis

机译:使用碳离子放射治疗剂量分布的比较与慢性血管侵袭肝细胞癌的强度调制放射治疗:回顾性分析

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摘要

Background/Aim: This study compared the dose distributions of carbon ion radiotherapy (C-ion RT) and intensity-modulated radiotherapy (IMRT) in patients with locally advanced hepatocellular carcinoma (LAHCC). Patients and Methods: A retrospective analysis was conducted in 10 consecutive patients with LAHCC who had undergone C-ion RT. The dose-volume histogram parameters of clinical plans using C-ion RT at 60 Gy and simulated plans using IMRT at 60 Gy and 50 Gy were compared. We measured the percentage of the normal liver volume that received at least 5 Gy (V-5), 10 Gy (V-10), 20 Gy (V-20), 30 Gy (V-30), 40 Gy (V-40), and 50 Gy (V-50). Results: The V-5, V-10, V-20, and the mean liver dose were significantly lower in patients who received 60 Gy of C-ion RT than in those who received 50 or 60 Gy of IMRT. Conclusion: C-ion RT exhibits a better liver dose distribution than IMRT in patients with LAHCC.
机译:背景/目的:该研究将碳离子放射疗法(C-ION RT)和强度调节放疗(IMRT)的剂量分布与局部晚期肝细胞癌(LAHCC)进行比较。 患者和方法:回顾性分析在连续10名患有C-ION RT的LAHCC患者中进行。 比较了使用60 GY和50 GY的60 GY和模拟计划的C-ION RT的临床计划的剂量直方图参数。 我们测量了接受至少5 GY(V-5),10GY(V-10),20 Gy(V-20),30Gy(V-30),40 Gy(V-)的正常肝体积的百分比 40)和50 GY(V-50)。 结果:V-5,V-10,V-20和平均肝剂量在接受60 GY的C-ION RT的患者中显着低于接受50或60 GY的IMRT的患者。 结论:C-ION RT表现出比LAHCC患者的IMRT更好的肝剂量分布。

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