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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Prognostic Value of Age and Distant Metastasis in Differentiated Thyroid Carcinoma Undergoing Salvage Surgery
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Prognostic Value of Age and Distant Metastasis in Differentiated Thyroid Carcinoma Undergoing Salvage Surgery

机译：经历裂解手术中的分化甲状腺癌中的年龄和远距离转移的预后价值

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Aim: To investigate the association between survival outcomes and clinicopathological factors, including pathological restaging based on the UICC8th, among patients with recurrence differentiated thyroid carcinoma undergoing salvage surgery of local site. Patients and Methods: A total of 54 patients who underwent salvage surgery of local site for recurrence differentiated thyroid carcinoma were enrolled. The optimal cutoff ages at salvage surgery for predicting death and cancer-specific death were determined by receiver operating curve analysis. Overall and cancer-specific survivals were determined using log-rank test and Cox's proportional hazards model. Results: Univariate analysis showed that age and the presence of distant metastasis at salvage surgery were significantly associated with overall survival (p=0.01 and p = 65 years and the presence of distant metastasis were significantly associated with shorter overall survival (p<0.01 and p=0.03, respectively) and shorter cancer-specific survival (p<0.01 and p=0.01, respectively). Conclusion: Older age and the presence of distant metastasis at salvage surgery of local site were identified as predictors for poor survival outcomes in recurrence differentiated thyroid carcinoma.
机译：目的：探讨生存结果和临床病理因子之间的关联，包括基于UICC8th的病理重新恢复，患有局部遗址的复制术治疗梳理手术的患者。患者和方法：共有54例接受局部遗产局部营养的患者进行复发分化的甲状腺癌。通过接收器操作曲线分析确定了预测死亡和癌症特异性死亡的最佳截止年龄。使用对数秩检验和COX的比例危险模型确定总体和癌症特异性幸存者。结果：单变量分析表明，拯救手术的年龄和存在远处转移的存在显着与整体存活有显着相关（P = 0.01和P = 65岁，并且远离转移的存在与整体存活较短相关（P <0.01和p分别= 0.03分别较短的癌症存活率（P <0.01和P = 0.01）。结论：年龄较大的年龄和局部拯救局部抢救手术的存在作为预测因子，用于复发中的存活率不佳甲状腺癌。

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