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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >The Impact of Intraoperative Blood Loss on the Long-term Prognosis after Curative Resection for Borrmann Type IV Gastric Cancer: A Retrospective Multicenter Study
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The Impact of Intraoperative Blood Loss on the Long-term Prognosis after Curative Resection for Borrmann Type IV Gastric Cancer: A Retrospective Multicenter Study

机译:术后失血对博勒姆纳型胃癌治疗切除长期预后的影响:回顾性多中心研究

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摘要

Background/Aim: To evaluate the outcomes of curative resection for Borrmann type IV gastric cancer through an analysis of the clinical, surgical and pathological data and through identifying which of these prognostic factors are associated with survival. Patients and Methods: We retrospectively analyzed 2798 patients who had undergone excision of the primary lesion and 122 patients with type IV gastric cancer undergoing curative resection (R0 or 1) at Yokohama City University Hospital and Kanagawa Cancer Center between November 1995 and May 2016. Results: Borrmann type IV gastric cancer had more advanced and unfavorable clinicopathological factors compared to other types. The 5-year overall survival rate was 28%, and the median survival was 21.8 months. The overall survival rate was influenced by the depth of invasion, lymph node metastasis, peritoneal lavage cytology (CY), stage and intraoperative blood loss. Of these, independent prognostic factors were intraoperative blood loss ( = 400 ml, risk ratio 1.64; p=0.045) and CY (0 vs. 1, risk ratio 2.25; p=0.004). Conclusion: The control of intraoperative bleeding had a positive impact on the survival of patients receiving curative resection for Borrmann type IV gastric cancer.
机译:背景/目的:通过分析临床,外科和病理数据,评价Borrmann型IV胃癌治疗结果的结果,并通过鉴定这些预后因素中的哪一个与存活相关。患者和方法:我们回顾性分析了2798例经历了初级病变切换的患者和122例患有IV型胃癌患者(R0或1)的横滨市1995年11月至2016年5月的患者患有治疗切除(R0或1)的患者。结果:与其他类型相比,Borrmann型胃癌具有更先进和不利的临床病理因素。 5年的总生存率为28%,中位存活率为21.8个月。整体存活率受到侵袭深度,淋巴结转移,腹膜灌洗细胞学(CY),阶段和术中失血的影响。其中,独立的预后因素是术中失血(= 400毫升,风险比1.64; p = 0.045)和Cy(0 vs.1,风险比2.25; P = 0.004)。结论:对术中出血的控制对博勒姆纳型胃癌接受治疗切除患者的生存产生了积极影响。

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