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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Whole-brain Radiation Therapy for Breast Cancer Patients with Dural Metastasis Without Concomitant Brain Metastasis and Leptomeningeal Metastasis
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Whole-brain Radiation Therapy for Breast Cancer Patients with Dural Metastasis Without Concomitant Brain Metastasis and Leptomeningeal Metastasis

机译：乳腺癌患者的全脑放射治疗无伴随脑转移和Leptomenenal Metastasis

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Aim: To evaluate outcomes of breast cancer patients with confirmed dural metastasis (DM) alone who received whole-brain radiation therapy (WBRT). Patients and Methods: The medical records of thirty-three breast cancer patients who received WBRT to treat intracranial metastasis were retrospectively reviewed. The clinical presentation of DM-only was compared with that of brain metastasis (BM)/leptomeningeal metastasis (LM). Results: Eight patients had DM and 25 patients had BM/LM. Median survival was 12 months in patients with DM and 7 months in those with BM/LM. Multivariate analysis found that only a Karnofsky performance status of = 70 was significantly associated with improved OS. DM did not cause the death of any patient. Symptoms did not worsen in any DM patient. Conclusion: WBRT can be considered for patients with DM alone for symptom improvement and preventing DM-related death.
机译：目的：评估乳腺癌患者的乳腺癌患者的结果，确认的多云转移（DM）接受全脑放射治疗（WBRT）。 患者及方法：回顾性审查了接受WBRT治疗颅内转移的三十三名乳腺癌患者的病态。 DM-POPLE的临床介绍与脑转移（BM）/ Leptomeneneal转移（LM）进行了比较。 结果：8名患者患有DM和25名患者的BM / LM。 中位数生存率为12个月，患者在DM和7个月内患有BM / LM。 多变量分析发现，只有Karnofsky的性能状态＆ = 70显着与改进的操作系统有显着相关。 DM没有导致任何患者的死亡。 症状在任何DM患者中都不会恶化。 结论：单独DM患者可以考虑WBRT用于症状改善和预防DM相关死亡。

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