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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Collision Tumors of the Gastrointestinal Tract: A Systematic Review of the Literature
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Collision Tumors of the Gastrointestinal Tract: A Systematic Review of the Literature

机译:胃肠道的碰撞肿瘤:对文献的系统审查

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Background/Aim: Collision tumors are rare neoplasms which consist of two or more distinct neoplasms that develop adjacent to one another and coexist with no or minimal intermingling between them. Their diagnosis is often incidental and their behavior remains widely unknown. Several theories have been proposed regarding their pathogenesis. The objective of this study was the evaluation of current evidence on collision tumors of the gastrointestinal tract regarding their pathology, biological behavior and treatment approach. Materials and Methods: The PubMed and Cochrane bibliographical databases were searched from January 1997 to July 2018 (last search: July 5th, 2018) for studies reporting on collision tumors of the gastrointestinal tract that also included a therapeutic approach. Results: Forty-seven studies reporting on collision tumors of the gastrointestinal tract were identified. They reported collectively on 53 cases (43 males, 10 females) with collision tumors of the esophagus, stomach, small intestine and large intestine. The vast majority (96.2%) of tumors consisted of two distinct histological components and only two cases involved a greater number of histological subtypes. Fifty-one patients underwent a surgical or endoscopic tumor resection, accompanied in 22 cases by adjuvant or neoadjuvant therapy. The remaining two patients underwent palliative operations. In total, three patients experienced immediate postoperative complications. Conclusion: Collision tumors of the gastrointestinal tract, despite their rare nature, constitute a quite interesting field of study. This review offers a thorough insight into the clinicopathological characteristics and biological behavior of these rare tumors.
机译:背景/目的:碰撞肿瘤是罕见的肿瘤,其由两个或更多个不同的肿瘤组成,它们彼此相邻和它们之间的邻近和它们共存。他们的诊断通常是偶然的,他们的行为仍然不为人知。已经提出了几种理论,关于其发病机制。本研究的目的是评估目前关于胃肠道碰撞肿瘤关于其病理学,生物行为和治疗方法的疾病。材料和方法:从1997年1月到2018年1月至2018年7月(2018年7月5日)的研究报告了胃肠道碰撞肿瘤的研究,这些数据库是从胃肠道的碰撞肿瘤的研究。结果:鉴定了关于胃肠道碰撞肿瘤的四十七项研究。他们在53例(43名男性,10名女性)中统称,具有食道,胃,小肠和大肠的碰撞肿瘤。绝大多数(96.2%)肿瘤由两个不同的组织学成分组成,只有两种情况涉及更多的组织学亚型。五十一名患者经过外科手术或内窥镜肿瘤切除,伴有佐剂或Neoadjuvant治疗的22例。剩下的两名患者接受了姑息作业。总共有三名患者经历了立即术后并发症。结论:胃肠道碰撞肿瘤,尽管它们罕见的自然,构成了一个非常有趣的研究领域。本综述对这些稀有肿瘤的临床病理特征和生物学行为提供了全面的洞察力。

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