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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >A Scoring System to Predict the Development of Bone Metastasis After Radical Resection of Colorectal Cancer
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A Scoring System to Predict the Development of Bone Metastasis After Radical Resection of Colorectal Cancer

机译：预测结直肠癌根治性切除后骨转移发展的评分系统

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Background/Aim: To develop a scoring system to predict bone metastasis after radical resection within 5 years. Patients and Methods: We evaluated the patient records of 1,749 patients, of whom 50 patients developed bone metastasis. Treatment-related factors (age, gender, localization, histology, preoperative carbohydrate antigen 199 level, T-stage, lymph node metastasis (LN) and pulmonary metastasis (PM)) were analyzed. Results: We found three independent risk factors, namely rectal cancer (p= 0.038), LN (p= 0.006) and metachronous PM (p< 0.001). Scoring was conducted by adding zero or one point from each variable and resulted in four groups of 0, 1, 2 or 3 points. Three groups were formed, with 0-1 points vs. 2 points vs. 3 points (1.5% vs. 6.6% and 10.5%, p< 0.001). Conclusion: This new score can help clinicians identify patients at risk for continuous monitoring and optimize surveillance to be able to detect and treat bone metastases very early in order to avoid skeletal complications.
机译：背景/目的：在5年内开发评分系统以预测激进切除后的骨转移。患者和方法：我们评估了1,749名患者的患者记录，其中50名患者发生骨转移。分析了治疗相关因素（年龄，性别，定位，组织学，分析术前碳水化合物抗原199级，T-阶段，淋巴结转移（LN）和肺转移（PM））。结果：我们发现三种独立的危险因素，即直肠癌（P = 0.038），LN（P = 0.006）和比较PM（P <0.001）。通过从每个变量添加零或一个点来进行评分，并导致四组0,1,2或3点。形成了三组，含量为0-1点与2点与3分（1.5％vs.6.6％和10.5％，P <0.001）。结论：这种新分数可以帮助临床医生识别患者的患者进行连续监测和优化监测，以便能够很早地检测和治疗骨转移，以避免骨骼并发症。

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