The bla(NDM-1)-Carrying IncA/C-2 Plasmid Underlies Structural Alterations and Cointegrate Formation In Vivo

Hadziabdic Sead; Fischer Jennie; Borowiak Maria; Malorny Burkhard; Juraschek Katharina; Kaesbohrer Annemarie; Guerra Beatriz; Deneke Carlus; Gonzalez-Zorn Bruno; Szabo Istvan

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The bla(NDM-1)-Carrying IncA/C-2 Plasmid Underlies Structural Alterations and Cointegrate Formation In Vivo

机译：BLA（NDM-1） - 克里宁INCA / C-2质粒下潜结构改变和体内共同组合形成

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In 2012, a carbapenemase-producing Salmonella enterica serovar Corvallis isolate carrying a bla(NDM-1), multiresistance IncA/C-2 plasmid, apart from IncHI2 and ColE-like plasmids, was detected in a wild bird in Germany. In a recent broiler chicken infection study, we observed transfer of this bla(NDM-1)-carrying IncA/C-2 plasmid to other Enterobacteriaceae. Here, we focused on the stability of this plasmid and gained insight into the type and frequency of its structural alterations after an in vivo passage in a broiler chicken infection study.

机译：2012年，在德国的野生鸟类中检测到携带BLA（NDM-1），携带BLA（NDM-1）的碳结构酶的沙门氏菌肠道Servalla肠道肠道肠道肠道肠道肠道肠道肠溶蛋虫Corvallis。在最近的肉鸡感染研究中，我们观察到这种BLA（NDM-1）的转移 - 将INCA / C-2质粒转移到其他肠杆菌中。在这里，我们专注于这种质粒的稳定性，并且在肉鸡鸡感染研究中的体内通道中获得了其结构改变的类型和频率的洞察力。

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来源
《Antimicrobial agents and chemotherapy.》 |2019年第8期|共1页
作者
Hadziabdic Sead; Fischer Jennie; Borowiak Maria; Malorny Burkhard; Juraschek Katharina; Kaesbohrer Annemarie; Guerra Beatriz; Deneke Carlus; Gonzalez-Zorn Bruno; Szabo Istvan;
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作者单位

German Fed Inst Risk Assessment BfR Dept Biol Safety Berlin Germany;

German Fed Inst Risk Assessment BfR Dept Biol Safety Berlin Germany;

German Fed Inst Risk Assessment BfR Dept Biol Safety Berlin Germany;

German Fed Inst Risk Assessment BfR Dept Biol Safety Berlin Germany;

German Fed Inst Risk Assessment BfR Dept Biol Safety Berlin Germany;

German Fed Inst Risk Assessment BfR Dept Biol Safety Berlin Germany;

European Food Safety Author Parma Italy;

German Fed Inst Risk Assessment BfR Dept Biol Safety Berlin Germany;

Univ Complutense Madrid Fac Vet Dept Sanidad Anim Madrid Spain;

German Fed Inst Risk Assessment BfR Dept Biol Safety Berlin Germany;

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原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
NDM-1 carbapenemases; Salmonella; broiler chicken infection study;

机译：NDM-1碳结氨酸酶;沙门氏菌;肉鸡鸡感染研究;

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1. The bla(NDM-1)-Carrying IncA/C-2 Plasmid Underlies Structural Alterations and Cointegrate Formation In Vivo [J] . Hadziabdic Sead, Fischer Jennie, Borowiak Maria, Antimicrobial agents and chemotherapy. . 2019,第8期

机译：BLA（NDM-1） - 克里宁INCA / C-2质粒下潜结构改变和体内共同组合形成
2. IncA/C Plasmid Carrying bla(NDM-1), bla(CMY-16), and fosA3 in a Salmonella enterica Serovar Corvallis Strain Isolated from a Migratory Wild Bird in Germany [J] . Villa L., Guerra B., Schmoger S., Antimicrobial agents and chemotherapy. . 2015,第10期

机译：IncA / C质粒携带bla（NDM-1），bla（CMY-16）和fosA3在德国沙门氏菌中从迁徙野生鸟类中分离出来的肠道沙门氏菌Corvallis菌株中
3. Evolution of IncA/C bla CMY-2-carrying plasmids by acquisition of the bla NDM-1 carbapenemase gene [J] . CarattoliA., VillaL., PoirelL., Antimicrobial agents and chemotherapy. . 2012,第2期

机译：通过收购bla NDM-1碳青霉烯酶基因来进化IncA / C bla CMY-2载体质粒
4. The Structural Information and Alteration Information Extraction and Metallogenic Prognosis in Laos Area [C] . Wenlan Liu, Gongwen Wang, Yongqing Chen International Conference on Environmental Science and Information Application Technology . 2013

机译：老挝地区的结构信息和改变信息提取和成矿预后
5. Effect of structural deformation on the petrology and distribution of diagenetic alteration within the Oriskany Sandstone in Little Mountain Anticline of the Smoke Hole Region of eastern West Virginia. [D] . Klipp, Brian Daniel. 2016

机译：结构变形对西维吉尼亚州东部烟洞地区小山脉背斜的Oriskany砂岩的岩石学和成岩蚀变分布的影响。
6. The blaNDM-1-Carrying IncA/C2 Plasmid Underlies Structural Alterations and Cointegrate Formation In Vivo [O] . Sead Hadziabdic, Jennie Fischer, Maria Borowiak, 2019

机译：blaNDM-1-Carrying IncA / C2质粒是结构改变和体内共整合形成的基础
7. Emergence of Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae Coharboring a bla NDM-1 -Carrying Virulent Plasmid and a bla KPC-2 -Carrying Plasmid in an Egyptian Hospital [O] . Mohamed Abd El-Gawad El-Sayed Ahmed, Yanxian Yang, Yongqiang Yang, 2021

机译：抗软化碳癌抗性肺炎的出现肺泡Coharboring A BLA NDM-1-古典毒性质粒和埃及医院的BLA KPC-2-晕蛋白

The bla(NDM-1)-Carrying IncA/C-2 Plasmid Underlies Structural Alterations and Cointegrate Formation In Vivo

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