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Green synthesis of CeO2 and Zr/Sn-dual doped CeO2 nanoparticles with photoantioxidant and antibiofilm activities

机译:CEO2和ZR / SN双掺杂CEO2纳米粒子的绿色合成,具有光析氧化剂和抗抗血栓活性

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Cerium oxide (CeO2) and 1%, 5% and 10% zirconium/tin-dual doped CeO2 nanoparticles (Zr/Sn-dual doped CeO2 NPs) were synthesized using an aqueous leaf extract of Pometia pinnata. By using UV-visible diffuse reflectance spectroscopy, the band gap energies of these materials were found to be in the range of similar to 2.49 to 2.66 eV. The average crystallite sizes of the fluorite phase obtained from X-ray diffraction were between 7 and 16 nm. X-ray photoelectron spectroscopy (XPS) analysis further confirmed the synthesis of CeO2 and Sn-doped CeO2 NPs. Almost spherical shapes of the nanomaterials with an average particle size of 12-17 nm were determined using scanning electron microscopy and transmission electron microscopy studies. Photoantioxidant activities of the synthesized materials showed enhanced photoantioxidant response under visible light irradiation in comparison with those under dark conditions in both dose- and time-dependent manner. The CeO2 NPs exhibited a significant concentration-dependent antibiofilm activity against the Gram-positive bacteria Staphylococcus aureus (S. aureus) and Listeria monocytogenes (L. monocytogenes). Only the 10% Zr/Sn-dual doped-CeO2 NPs were found to inhibit S. aureus biofilm formation at higher concentrations. All Zr/Sn-dual doped CeO2 NPs exhibited a concentration-dependent biofilm inhibition of L. monocytogenes and also bactericidal activity towards S. aureus. These nanomaterials exhibited enhanced photoantioxidant activities and antibacterial properties, which make them suitable for various biological applications.
机译:使用PARMIA PINNATA的含水叶提取物合成,合成氧化铈(CEO2)和1%,5%和10%锆/锡 - 双掺杂CEO2纳米颗粒(Zr / Sn-Dual掺杂CeO2 NPS)。通过使用UV可见的漫反射光谱,这些材料的带隙能量被发现在类似于2.49至2.66eV的范围内。从X射线衍射获得的氟磷的平均微晶尺寸在7至16nm之间。 X射线光电子能谱(XPS)分析进一步证实了CeO2和Sn-掺杂CeO2 NPS的合成。使用扫描电子显微镜和透射电子显微镜研究确定平均粒径为12-17nm的纳米材料的几乎球形。合成材料的光学氧化活性显示出可见光照射下的显着的光反应,与暗条件下的剂量和时间依赖性方式相比。 CEO2 NPS表现出对革兰氏阳性细菌金黄色葡萄球菌(S.UUREUS)和李斯特菌单核细胞增生(L.单核细胞增生)的显着浓度依赖性抗血栓活性。仅发现10%Zr / Sn-DOUAL-CEO2 NPS以更高浓度抑制S.UUREUS生物膜形成。所有Zr / Sn - 双掺杂CeO2 NPS表现出L.单核细胞增生的浓度依赖性生物膜抑制,也朝向金黄色葡萄球菌的杀菌活性。这些纳米材料表现出增强的光反氧化活性和抗菌性能,这使得它们适用于各种生物应用。

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