Biomaterial-based approaches to engineering immune tolerance

Amy E. Emerson; Emily M. Slaby; Shivani C. Hiremath; Jessica D. Weaver

首页> 外文期刊>Biomaterials Science >Biomaterial-based approaches to engineering immune tolerance

【24h】

Biomaterial-based approaches to engineering immune tolerance

机译：基于生物材料的免疫耐受性方法

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The development of biomaterial-based therapeutics to induce immune tolerance holds great promise for the treatment of autoimmune diseases, allergy, and graft rejection in transplantation. Historical approaches to treat these immunological challenges have primarily relied on systemic delivery of broadlyacting immunosuppressive agents that confer undesirable, off-target effects. The evolution and expansion of biomaterial platforms has proven to be a powerful tool in engineering immunotherapeutics and enabled a great diversity of novel and targeted approaches in engineering immune tolerance, with the potential to eliminate side effects associated with systemic, non-specific immunosuppressive approaches. In this review, we summarize the technological advances within three broad biomaterials-based strategies to engineering immune tolerance: nonspecific tolerogenic agent delivery, antigen-specific tolerogenic therapy, and the emergent area of tolerogenic cell therapy.

机译：生物材料治疗诱导免疫耐受性的发展对移植过程中的自身免疫疾病，过敏和移植物排斥的治疗具有很大的承担。治疗这些免疫挑战的历史方法主要依赖于赋予赋予不良的免疫抑制剂的全身递送，这些免疫抑制剂赋予不良的偏离目标影响。生物材料平台的演变和扩展已被证明是工程免疫治疗方法的强大工具，使工程免疫耐受性具有大量的新颖和有针对性的方法，可能会消除与系统性，非特异性免疫抑制方法相关的副作用。在本综述中，我们总结了三种基于生物材料的技术进步，以工程免疫耐受性：非特异性耐受性药剂递送，抗原特异性耐受性治疗和耐受性细胞疗法的突出区域。

著录项

来源
《Biomaterials Science》 |2020年第24期|共19页
作者
Amy E. Emerson; Emily M. Slaby; Shivani C. Hiremath; Jessica D. Weaver;
展开▼
作者单位

School of Biological and Health Systems Engineering Arizona State University Tempe AZ USA;

School of Biological and Health Systems Engineering Arizona State University Tempe AZ USA;

School of Biological and Health Systems Engineering Arizona State University Tempe AZ USA;

School of Biological and Health Systems Engineering Arizona State University Tempe AZ USA;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类计量学;
关键词

相似文献

外文文献
中文文献
专利

1. Cross-immune tolerance: conception and its potential significance on transplantation tolerance [J] . Yong Zhao, Xianchang Li 中国免疫学杂志（英文版） . 2010,第001期
2. Cross-immune tolerance:conception and its potential significance on transplantation tolerance [J] . Yong Zhao, Xianchang Li 细胞与分子免疫学：英文版 . 2010,第001期
3. Cellular and molecular mechanisms breaking immune tolerance in inborn errors of immunity [J] . Georgios Sogkas, Faranaz Atschekzei, Ignatius Ryan Adriawan, 细胞与分子免疫学：英文版 . 2021,第005期
4. Immune system modifications and feto-maternal immune tolerance [J] . Song Dan, Shi Yichao 中华医学杂志（英文版） . 2014,第017期
5. Flooding Tolerance in Rice: Focus on Mechanisms and Approaches [J] . Debabrata PANDA, Jijnasa BARIK 水稻科学（英文版） . 2021,第001期
6. Cell and biomaterial-based approaches to uterus regeneration [J] . Feiran Liu, Shiqi Hu, Shaowei Wang, Regenerative Biomaterials . 2019,第3期

机译：基于细胞和生物材料的子宫再生方法
7. Current approaches in biomaterial-based hematopoietic stem cell niches [J] . Bello Alvin Bacero, Park Hansoo, Lee Soo-Hong Acta biomaterialia . 2018,第期

机译：基于生物材料造血干细胞耐药性的电流方法
8. Ophthalmic Biomaterials SIG Update: UPDATE FROM THE OPHTHALMIC BIOMATERIALS SIGI PROGRESS IN BIOMATERIAL-BASED APPROACHES FOR IMPROVED TREATMENT OF OCULAR TRAUMA [J] . Michael A.Washington, Morgan V.Fedorchak Biomaterials Forum . 2018,第4期

机译：眼科生物材料SIG更新：从眼科生物材料的更新以生物材料的方法进行改善治疗眼外伤的方法
9. Understanding Systemic Immune Dysregulation in Severe Trauma and the Effects of Biomaterial-based Interventions [C] . Casey Vantucci, Laxminarayanan Krishnan, Albert Cheng, Society for Biomaterials annual meeting and exposition . 2018

机译：了解严重创伤中的全身免疫失调和基于生物材料的干预措施的影响
10. Gene Therapy Approaches to Immune Tolerance Induction in Canine Hemophilia [D] . French, Robert A. 2018

机译：犬血友病中免疫耐受性诱导的基因治疗方法
11. Graft Engineering and Adoptive Immunotherapy: New Approaches to Promote Immune Tolerance After Hematopoietic Stem Cell Transplantation [O] . Alice Bertaina, Maria Grazia Roncarolo -1

机译：移植工程和过继免疫治疗：造血干细胞移植后提高免疫耐受性的新方法
12. Repair strategies for traumatic spinal cord injury, with special emphasis on novel biomaterial-based approaches [O] . S. Soares, Y. von Boxberg, F. Nothias 2020

机译：创伤性脊髓损伤的修复策略，特别强调新型生物材料的方法
13. Targeting Tim-1 to Circumvent Immune Tolerance in Prostate Cancer. [R] . Arredouani, M. S. 2012

机译：针对Tim-1以减少前列腺癌中的免疫耐受。

Biomaterial-based approaches to engineering immune tolerance

摘要

著录项

相似文献

相关主题

期刊订阅