首页> 外文期刊>British Journal of Radiology >Unified platform for multimodal voxel-based analysis to evaluate tumour perfusion and diffusion characteristics before and after radiation treatment evaluated in metastatic brain cancer
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Unified platform for multimodal voxel-based analysis to evaluate tumour perfusion and diffusion characteristics before and after radiation treatment evaluated in metastatic brain cancer

机译:基于多式体素的分析统一平台,评价在转移性脑癌中评估的辐射治疗前后的肿瘤灌注和扩散特性

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摘要

Objective: Early changes in tumour behaviour following stereotactic radiosurgery) are potential biomarkers of response. To-date quantitative model-based measures of dynamic contrast-enhanced (DCE) and diffusion-weighted (DW) MRI parameters have shown widely variable findings, which may be attributable to variability in image acquisition, post-processing and analysis. Big data analytic approaches are needed for the automation of computationally intensive modelling calculations for every voxel, independent of observer interpretation.
机译:目的:立体定向放射外科术后肿瘤行为的早期变化是潜在的反应生物标志物。 基于日期的动态对比度增强(DCE)和扩散加权(DW)MRI参数的基于定量模型的措施已经显示出广泛的可变结果,其可归因于图像采集,后处理和分析的可变性。 对于每个体素的计算密集型建模计算,无论观察者解释都无关,需要大数据分析方法。

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