Regulation of chromatin structure and function: insights into the histone chaperone FACT

Wang Peijun; Yang Wanting; Zhao Shuxin; Nashun Buhe

首页> 外文期刊>Cell cycle >Regulation of chromatin structure and function: insights into the histone chaperone FACT

【24h】

Regulation of chromatin structure and function: insights into the histone chaperone FACT

机译：染色质结构和功能的调节：洞察组蛋白伴侣的事实

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

In eukaryotic cells, changes in chromatin accessibility are necessary for chromatin to maintain its highly dynamic nature at different times during the cell cycle. Histone chaperones interact with histones and regulate chromatin dynamics. Facilitates chromatin transcription (FACT) is an important histone chaperone that plays crucial roles during various cellular processes. Here, we analyze the structural characteristics of FACT, discuss how FACT regulates nucleosome/chromatin reorganization and summarize possible functions of FACT in transcription, replication, and DNA repair. The possible involvement of FACT in cell fate determination is also discussed.

机译：在真核细胞中，染色质可及性的改变对于染色质在细胞周期的不同时间保持其高度动态性质是必要的。组蛋白伴侣与组蛋白相互作用并调节染色质动力学。促进染色质转录（FACT）是一种重要的组蛋白伴侣，在各种细胞过程中发挥关键作用。在这里，我们分析FACT的结构特征，讨论FACT如何调节核小体/染色质重组，并总结FACT在转录、复制和DNA修复中的可能功能。还讨论了FACT在细胞命运决定中的可能作用。

著录项

来源
《Cell cycle》 |2021年第6期|共15页
作者
Wang Peijun; Yang Wanting; Zhao Shuxin; Nashun Buhe;
展开▼
作者单位

Inner Mongolia Univ Sch Life Sci State Key Lab Reprod Regulat &

Breeding Grassland Hohhot;

Inner Mongolia Univ Sch Life Sci State Key Lab Reprod Regulat &

Breeding Grassland Hohhot;

Inner Mongolia Univ Sch Life Sci State Key Lab Reprod Regulat &

Breeding Grassland Hohhot;

Inner Mongolia Univ Sch Life Sci State Key Lab Reprod Regulat &

Breeding Grassland Hohhot;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类细胞生物学;
关键词
Histone chaperone; FACT; chromatin dynamics; cell fate;

机译：组蛋白伴侣;事实;染色质动力学;细胞命运;

相似文献

外文文献
中文文献
专利

1. Histone chaperone FACT and curaxins: effects on genome structure and function [J] . Han-Wen Chang, Ekaterina V.Nizovtseva, Sergey V.Razin, 癌症转移与治疗（英文版） . 2019,第011期
2. Histone chaperone FACT and curaxins: effects on genome structure and function [J] . Han-Wen Chang, Ekaterina V.Nizovtseva, Sergey V.Razin, 癌症转移与治疗：英文版 . 2019,第011期
3. Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b [J] . Qi Zhang, Shankang Qi, Mingchu Xu, 细胞研究（英文版） . 2013,第002期
4. Biological function and regulation of histone and non-histone lysine methylation in response to DNA damage [J] . Yongcan Chen, Wei-Guo Zhu 生物化学与生物物理学报：英文版 . 2016,第007期
5. Regulation of chromatin by histone modifications [J] . Andrew J Bannister, Tony Kouzarides 细胞研究：英文版 . 2011,第003期
6. Regulation of Angiogenesis by Histone Chaperone HIRA-mediated Incorporation of Lysine 56-acetylated Histone H3.3 at Chromatin Domains of Endothelial Genes [J] . Debasree Dutta, Soma Ray, Pratik Home, The Journal of biological chemistry . 2010,第53期

机译：由组蛋白伴侣Hira介导的血管生成的血管生成的调节掺入赖氨酸56-乙酰化组蛋白H3.3在内皮基因染色质域的染色体域
7. Histone chaperone FACT FAcilitates Chromatin Transcription: mechanistic and structural insights [J] . Zhou Keda, Liu Yang, Luger Karolin Current Opinion in Structural Biology . 2020,第1期

机译：组蛋白伴侣的事实有助于染色质转录：机械和结构见解
8. Structure of the histone chaperone Asf1 bound to the histone H3C-terminal helix and functional insights [J] . Agez M, Chen J, Guerois R, Structure . 2007,第2期

机译：组蛋白伴侣ASF1的结构绑定到组蛋白H3C末端螺旋和功能的见解。
9. Role of the structural domains of linker histones and histone H3 in the chromatin fiber structure at low-ionic strength: scanning force microscopy (SFM) studies on partially trypsinized chromatin [C] . Jordanka Zlatanova, Sanford S. Leuba, Carlos J. Bustamante, Conference on Scanning Probe Microscopies . 1995

机译：在低离子强度下，在染色蛋白纤维结构中的关系结构域和组蛋白H3的作用：部分胰蛋白酶化染色质的扫描力显微镜（SFM）研究
10. Structure-Function Analysis of the Conserved Histone Chaperone Spt6. [D] . Loeliger, Erin Michelle. 2014

机译：保守组蛋白伴侣蛋白Spt6的结构-功能分析。
11. Regulation of Angiogenesis by Histone Chaperone HIRA-mediated Incorporation of Lysine 56-acetylated Histone H3.3 at Chromatin Domains of Endothelial Genes [O] . Debasree Dutta, Soma Ray, Pratik Home, 2010

机译：通过组蛋白伴侣HIRA介导的内皮基因染色质域中的赖氨酸56-乙酰化组蛋白H3.3整合血管生成的调控。
12. Regulation of Angiogenesis by Histone Chaperone HIRA-mediated Incorporation of Lysine 56-acetylated Histone H3.3 at Chromatin Domains of Endothelial Genes* [O] . Dutta, Debasree, Ray, Soma, Home, Pratik, 2010

机译：组蛋白伴侣HIRA介导的内皮基因染色质域中赖氨酸56-乙酰化组蛋白H3.3的掺入对血管生成的调控*
13. Chromatin Regulation of Estrogen-Mediated Transcription in Breast Cancer: Rules for Binding Sites in Nucleosomes and Modified Histones that Enhance ER Binding [R] . Chrivia, J. C. 2005

机译：染色质调节乳腺癌中雌激素介导的转录：核小体中结合位点的规则和增强ER结合的修饰组蛋白

Regulation of chromatin structure and function: insights into the histone chaperone FACT

摘要

著录项

相似文献

相关主题

期刊订阅