Energy metabolism as a regulator of ferroptosis

Ma Yanhong; Han Fei; Min Junxia; Lin Weiqiang

首页> 外文期刊>Cell cycle >Energy metabolism as a regulator of ferroptosis

【24h】

Energy metabolism as a regulator of ferroptosis

机译：能量代谢作为硬化症的调节剂

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Ferroptosis is a newly identified form of cell death that is regulated by many metabolic pathways, including iron, lipid and amino acids. Recent two studies reveal that the mitochondria and energy stress could also mediate ferroptosis. Gao et al. report that mitochondria play an essential role in ferroptosis induced by cysteine deprivation. In addition, Lee et al. show that energy stress depressed ferroptosis partly through activation of AMP-activated protein kinase. These findings provide potential therapeutic strategies for treating ferroptosis-related diseases, such as cancer, tissue injury and neurodegenerative diseases.

机译：铁下垂是一种新发现的细胞死亡形式，受多种代谢途径调节，包括铁、脂质和氨基酸。最近的两项研究表明，线粒体和能量应激也可能介导铁下垂。Gao等人报道，线粒体在半胱氨酸剥夺诱导的铁下垂中起着重要作用。此外，Lee等人表明，能量应激部分通过激活AMP激活的蛋白激酶来抑制铁下垂。这些发现为治疗与铁下垂相关的疾病提供了潜在的治疗策略，如癌症、组织损伤和神经退行性疾病。

著录项

来源
《Cell cycle》 |2020年第22期|共3页
作者
Ma Yanhong; Han Fei; Min Junxia; Lin Weiqiang;
展开▼
作者单位

Zhejiang Univ Affiliated Hosp 1 Kidney Dis Ctr Sch Med Hangzhou Zhejiang Peoples R China;

Zhejiang Univ Affiliated Hosp 1 Kidney Dis Ctr Sch Med Hangzhou Zhejiang Peoples R China;

Zhejiang Univ Affiliated Hosp 1 Inst Translat Med Sch Med Hangzhou Peoples R China;

Zhejiang Univ Affiliated Hosp 4 Inst Translat Med Sch Med Hangzhou Peoples R China;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类细胞生物学;
关键词
Ferroptosis; mitochondria; energy stress;

机译：骨凋亡;线粒体;能量压力;

相似文献

外文文献
中文文献
专利

1. Supplementation of branched-chain amino acids in protein-restricted diets modulates the expression levels of amino acid transporters and energy metabolism associated regulators in the adipose tissue of growing pigs [J] . Yinghui Li, Hongkui Wei, Fengna Li, 动物营养：英文版 . 2016,第001期
2. PPARs： diverse regulators in energy metabolism and metabolic diseases [J] . Yong-Xu Wang 细胞研究：英文版 . 2010,第002期
3. PPARs: diverse regulators in energy metabolism and metabolic diseases [J] . Yong-Xu Wang 细胞研究（英文版） . 2010,第002期
4. Identification of PRDX6 as a regulator of ferroptosis [J] . Bin Lu, Xiao-bing Chen, Yu-cai Hong, 中国药理学报：英文版 . 2019,第010期
5. Effects of Radix Aconiti Lateralis Preparata and Rhizoma Zingiberis on Energy Metabolism and Expression of the Genes Related to Metabolism in Rats [J] . YU Hua-yun, WANG Shi-jun, TENG Jia-lin, 中国结合医学杂志：英文版 . 2012,第001期
6. RF-amide related peptide-3 (RFRP-3): a novel neuroendocrine regulator of energy homeostasis, metabolism, and reproduction [J] . Anjum Shabana, Khattak Muhammad Nasir Khan, Tsutsui Kazuyoshi, Molecular biology reports . 2021,第2期

机译：RF-amide相关肽-3（RFRP-3）：一种新型能源稳态，新陈代谢和繁殖的新型神经内分泌调节因子
7. Functional genomic studies reveal the androgen receptor as a master regulator of cellular energy metabolism in prostate cancer [J] . Gonthier Kevin, Poluri Raghavendra Tejo Karthik, Audet-Walsh Etienne The Journal of Steroid Biochemistry and Molecular Biology . 2019,第期

机译：功能基因组研究显示前列腺癌中细胞能量代谢的雄激素受体
8. Cytosolic GAPDH as a redox-dependent regulator of energy metabolism [J] . Markus Schneider, Johannes Knuesting, Oliver Birkholz, BMC Plant Biology . 2018,第1期

机译：胞岩GapDH作为氧化还原依赖性能量代谢调节剂
9. Microwave field energy as baker's yeast metabolism regulator [C] . Morozov G.A., Krynitskiy P.P. International Conference on Antenna Theory and Techniques . 2015

机译：微波场能作为面包酵母的代谢调节剂
10. Protein Regulators of Lipid and Energy Metabolism [D] . Campbell, Latoya E. 2021

机译：脂质和能量代谢的蛋白质调节剂
11. Role of CRTC2 in Metabolic Homeostasis: Key Regulator of Whole-Body Energy Metabolism? [O] . Hye-Sook Han, Yongmin Kwon, Seung-Hoi Koo 2020

机译：CRTC2在代谢稳态中的作用：全身能量新陈代谢的关键调节因子吗？
12. Iron Deficiency and Neuroendocrine Regulators of Basal Metabolism, Body Composition and Energy Expenditure in Rats [O] . Jorge Moreno-Fernandez, Javier Díaz-Castro, María Alférez, 2019

机译：基础代谢的铁缺乏和神经内分泌调节剂，大鼠的身体成分和能量消耗
13. Scaffold Attachment Factor B1: A Novel Chromatin Regulator of Prostate Cancer Metabolism. [R] . You, S., Kim, J., Freeman, M. R. 2016

机译：支架附着因子B1：前列腺癌代谢的新型染色质调节剂。

Energy metabolism as a regulator of ferroptosis

摘要

著录项

相似文献

相关主题

期刊订阅