• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Applied Polymer Science >A poly(L-lactic acid) monofilament with high mechanical properties for application in biodegradable biliary stents
【24h】

A poly(L-lactic acid) monofilament with high mechanical properties for application in biodegradable biliary stents

机译：具有高机械性能的聚（L-乳酸）单丝，用于在可生物降解的胆尘支架中的应用

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In this article, a poly(L-lactic acid) (PLLA) monofilament with high mechanical properties which can be used to construct biodegradable biliary stents (BBS) is prepared. Compared with a commercial polydioxanone (PDO) suture, the PLLA monofilament has much higher Young's modulus. As a result, chronic outward force (COF) of the stent braided by PLLA monofilament is more than three times higher than that of the stent braided by PDO suture. Furthermore, by physicochemical indexes characterizations, it is acceptable that the PLLA monofilament has stable Young's modulus and higher elongation at break without brittle fracture risk during degradation in bile. In contrast, although PDO suture can also maintain Young's modulus well during degradation, its elongation at break is attenuated rapidly, which shows a high brittle fracture risk. These results indicate that PLLA monofilament is more suitable for constructing BBS with high COF, which are promising in treating more complex biliary strictures that need longer support time.
机译：本文制备了一种具有高力学性能的聚L-乳酸（PLLA）单丝，可用于构建可生物降解的胆道支架（BBS）。与商用聚二氧烷酮（PDO）缝合线相比，PLLA单丝具有更高的杨氏模量。结果表明，PLLA单丝编织支架的慢性外向力（COF）是PDO缝合支架的三倍以上。此外，通过物理化学指标表征，可以接受PLLA单丝具有稳定的杨氏模量和较高的断裂伸长率，在胆汁降解过程中没有脆性断裂风险。相比之下，虽然PDO缝合线在降解过程中也能很好地保持杨氏模量，但其断裂伸长率会迅速衰减，这表明其存在较高的脆性断裂风险。这些结果表明，PLLA单丝更适合构建具有高COF的BBS，在治疗需要更长支撑时间的更复杂胆管狭窄方面有希望。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号