A One Health Perspective for Defining and Deciphering Escherichia coli Pathogenic Potential in Multiple Hosts

Garcia Alexis; Fox James G.

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A One Health Perspective for Defining and Deciphering Escherichia coli Pathogenic Potential in Multiple Hosts

机译：用于在多个主机中定义和解密大肠杆菌致病潜力的一种健康观点

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E. coli is one of the most common species of bacteria colonizing humans and animals. The singularity of E. coli's genus and species underestimates its multifaceted nature, which is represented by different strains, each with different combinations of distinct virulence factors. In fact, several E. coli pathotypes, or hybrid strains, may be associated with both subclinical infection and a range of clinical conditions, including enteric, urinary, and systemic infections. E. coli may also express DNA-damaging toxins that could impact cancer development. This review summarizes the different E. coli pathotypes in the context of their history, hosts, clinical signs, epidemiology, and control. The pathotypic characterization of E. coli in the context of disease in different animals, including humans, provides comparative and One Health perspectives that will guide future clinical and research investigations of E. coli infections.

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《Comparative Medicine》 |2021年第1期|共43页
作者
Garcia Alexis; Fox James G.;
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作者单位

Univ Puerto Rico Mol Sci Res Ctr San Juan PR 00936 USA;

MIT Div Comparat Med Cambridge MA 02139 USA;

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正文语种 eng
中图分类畜牧、动物医学、狩猎、蚕、蜂;
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7. Deciphering the Cell Envelope Proteome of Escherichia coli [C] . M Papanastasiou, G Orfanoudaki, M Frantzeskos-Sardis, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

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机译：利用蛋白质组学质谱鉴别病原与非致病性耶尔森氏菌和大肠杆菌的比较

A One Health Perspective for Defining and Deciphering Escherichia coli Pathogenic Potential in Multiple Hosts

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