Neutrophilic asthma features increased airway classical monocytes

Niessen Natalie M.; Baines Katherine J.; Simpson Jodie L.; Scott Hayley A.; Qin Ling; Gibson Peter G.; Fricker Michael

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Neutrophilic asthma features increased airway classical monocytes

机译：中性哮喘具有增加的气道古典单核细胞

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Background Monocytes and macrophages are critical innate immune cells of the airways. Despite their differing functions, few clinical studies discriminate between them and little is known about their regulation in asthma.

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来源
《Clinical and experimental allergy :》 |2021年第2期|共13页
作者
Niessen Natalie M.; Baines Katherine J.; Simpson Jodie L.; Scott Hayley A.; Qin Ling; Gibson Peter G.; Fricker Michael;
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作者单位

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

Cent South Univ Dept Resp Med Xiangya Hosp Dept Pulm &

Crit Care Med Changsha Peoples R China;

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

Univ Newcastle Prior Res Ctr Hlth Lungs Newcastle NSW Australia;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
asthma; macrophage; mannose receptor; monocyte; neutrophil; severe asthma; sputum;

机译：哮喘;巨噬细胞;甘露糖受体;单核细胞;中性粒细胞;严重的哮喘;痰;

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1. Continuous positive airway pressure acutely increases exercise duration in children with severe therapy-resistant asthma:a randomized crossover trial [J] . Claudia Silva Schindel, Daniele Schiwe, Joao Paulo Heinzmann-Filho, 世界儿科杂志(英文版) . 2021,第002期
2. Sputum interleukin-17 is increased and associated with airway neutrophilia in patients with severe asthma [J] . SUN Yong-chang, ZHOU Qing-tao, YAO Wan-zhen 中华医学杂志（英文版） . 2005,第011期
3. Effects of Medication Use on Small Airway Function and Airway Inflammation in Patients with Clinically Controlled Asthma [J] . Yun LI, Hong-ying YU, Kao-chuang ZHAO, 当代医学科学(英文) . 2021,第004期
4. HMGB1 contributes to allergen-induced airway remodeling in a murine model of chronic asthma by modulating airway inflammation and activating lung fibroblasts [J] . Changchun Hou, Jinliang Kong, Yue Liang, 中国免疫学杂志（英文版） . 2015,第004期
5. NEUTROPHILIC INFLAMMATION OF THE UPPER AIRWAYS IS A CHARACTERISTIC FEATURE OF MACROLIDE RESPONDERS IN PATIENTS WITH ASTHMA [J] . Takeyama Kiyoshi, Akaba Tomohiro, Honda Nahoko, Respirology : . 2018,第Suppla2期

机译：上呼吸道的中性粒细胞炎症是哮喘患者的大环内酯响应者的特征
6. Combined Haemophilus influenzae respiratory infection and allergic airways disease drives chronic infection and features of neutrophilic asthma [J] . EssilfieA.-T., SimpsonJ.L., DunkleyM.L., Thorax: The Journal of the British Thoracic Society . 2012,第7期

机译：流感嗜血杆菌合并呼吸道感染和过敏性气道疾病可导致慢性感染和中性粒细胞性哮喘
7. Heterogeneity of Airway Inflammation in Persistent Asthma : Evidence of Neutrophilic Inflammation and Increased Sputum Interleukin-8 [J] . Peter G. Gibson Jodie L. Simpson and Nicholas Saltos Chest . 2001,第5期

机译：持续性哮喘患者气道炎症的异质性：中性粒细胞炎症和痰白细胞介素8升高的证据
8. Sputum Eosinophil Counts and Eosinophil Cationic Protein (ECP) Levels in Cough-Variant Asthma and in Classic Asthma, and Their Relationships to Airway Hypersensitivity or Maximal Airway Response to Methacholine [C] . Young Yoo, Young Yull Koh, Hee Kang Asia Pacific Congress of Allergology and Clinical Immunology . 2004

机译：痰嗜酸性粒细胞计数和嗜酸铈粒细胞阳离子蛋白（ECP）水平在咳嗽变异哮喘和经典的哮喘，以及它们与气道超敏反应或最大气道对甲磺酸的关系的关系
9. Evidence of an infectious asthma phenotype: Chlamydia a driven allergy and airway hyperresponsiveness in pediatric asthma. [D] . Patel, Katir K. 2013

机译：感染性哮喘表型的证据：衣原体是小儿哮喘中由过敏和气道高反应性引起的。
10. Airway monocyte modulation relates to tumour necrosis factor dysregulation in neutrophilic asthma [O] . Natalie M. Niessen, Peter G. Gibson, Jodie L. Simpson, 2021

机译：气道单核细胞调节涉及中性嗜患者肿瘤坏死因子诱导剂
11. Airway monocyte modulation relates to TNF dysregulation in neutrophilic asthma [O] . Natalie M. Niessen, Peter G. Gibson, Jodie L. Simpson, 2021

机译：气道单核细胞调节涉及中性嗜患者的TNF失调
12. Interactions between HIV-Infected Monocytes and the Extracellular Matrix:Increased Capacity of HIV-Infected Monocytes to Adhere to and Spread on Extracellular Matrix Associated with Changes in Extent of Virus Replication and Cytopathic Effects in Infected [R] . Dhawan, S., Vargo, M., Meltzer, M. S. 1992

机译：HIV感染的单核细胞与细胞外基质之间的相互作用：HIV感染的单核细胞增加容纳和扩散细胞外基质的能力与病毒复制程度和感染细胞病变效应的变化相关

Neutrophilic asthma features increased airway classical monocytes

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