Comparison and interpretability of the available urticaria activity scores

Hawro T.; Ohanyan T.; Schoepke N.; Metz M.; Peveling‐Oberhag A.; Staubach P.; Maurer M.; Weller K.

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Comparison and interpretability of the available urticaria activity scores

机译：可用荨麻活动活动分数的比较与解释

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Abstract The urticaria activity score ( UAS ) is the gold standard for assessing disease activity in patients with chronic spontaneous urticaria ( CSU ). Two different versions, the UAS 7 and UAS 7 TD , are currently used in clinical trials and routine care. To compare both versions and to obtain data on their interpretability, 130 CSU patients applied both versions and globally rated their disease activity as none, mild, moderate, or severe. UAS 7 and UAS 7 TD values correlated strongly ( r = .90, P .001). Interquartile ranges for UAS 7 and UAS 7 TD values for mild, moderate, and severe CSU were 11‐20 and 10‐24, 16‐30 and 16‐32, and 27‐37 and 28‐40. UAS 7 values were slightly, but significantly lower as compared to UAS 7 TD values (mean difference: 1.6 ± 4.6, P .001). This difference was driven by lower wheal subscores (2.1 ± 3.5, P .001) and was most pronounced in patients with severe CSU (2.5 ± 5.6, P .01). The UAS 7/ UAS 7 TD ratio was 0.96 ± 0.21 and did not differ significantly between mild, moderate, and severe CSU . Since the results of both UAS versions are comparable, we recommend the use of the UAS7, which is less burdensome in administration and scoring.

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来源
《Allergy》 |2018年第1期|共5页
作者
Hawro T.; Ohanyan T.; Schoepke N.; Metz M.; Peveling‐Oberhag A.; Staubach P.; Maurer M.; Weller K.;
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作者单位

Department of Dermatology and AllergyCharité ‐ Universit?tsmedizin BerlinBerlin Germany;

Department of Dermatology and AllergyCharité ‐ Universit?tsmedizin BerlinBerlin Germany;

Department of Dermatology and AllergyCharité ‐ Universit?tsmedizin BerlinBerlin Germany;

Department of Dermatology and AllergyCharité ‐ Universit?tsmedizin BerlinBerlin Germany;

Department of DermatologyUniversity Medical Center MainzMainz Germany;

Department of DermatologyUniversity Medical Center MainzMainz Germany;

Department of Dermatology and AllergyCharité ‐ Universit?tsmedizin BerlinBerlin Germany;

Department of Dermatology and AllergyCharité ‐ Universit?tsmedizin BerlinBerlin Germany;

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正文语种 eng
中图分类医学免疫学;
关键词
disease activity; patient‐reported outcomes; pruritus; urticaria; urticaria activity score;

机译：疾病活动;患者报告的结果;瘙痒;荨麻疹;荨麻疹活动得分;

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Comparison and interpretability of the available urticaria activity scores

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