Metformin: myths, misunderstandings and lessons from history

Gillian Shenfield

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Metformin: myths, misunderstandings and lessons from history

机译：二甲双胍：历史上的神话，误解和教训

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Clinical trials of new drugs may overstate efficacy and not identify adverse effects. It is therefore unusual for the passage of time to reveal that a drug is less toxic, has greater efficacy and a wider range of uses than first claimed. For decades,metformin was misunderstood, vilified and banned in many countries, but it is now one of the most prescribed drugs in the world. In 2010 there were more than 100 million prescriptions worldwide for metformin, alone and in combination tablets.

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来源
《Australian prescriber》 |2013年第2期|共2页
作者
Gillian Shenfield;
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作者单位

Consultant clinical pharmacologist Sydney;

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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
biguanides; lactic acidosis; type 2 diabetes;

机译：双胍;乳酸毒中毒;2型糖尿病;

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Metformin: myths, misunderstandings and lessons from history

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