...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>European journal of neurology: the official journal of the European Federation of Neurological Societies >Non‐alcoholic fatty liver disease is associated with stroke severity and progression of brainstem infarctions
【24h】

Non‐alcoholic fatty liver disease is associated with stroke severity and progression of brainstem infarctions

机译：非酒精性脂肪肝病与中风严重程度和脑干梗塞的进展有关

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background and purpose Non‐alcoholic fatty liver disease ( NAFLD ) is closely correlated to visceral obesity, dyslipidaemia, insulin resistance and type 2 diabetes mellitus. We sought to assess the association between a specific stroke subgroup, brainstem infarctions ( BSI s) and NAFLD . Furthermore, we evaluated whether NAFLD is an independent risk factor in patients with BSI s. Methods Non‐alcoholic fatty liver disease was assessed in 306 patients with radiologically confirmed BSI s via liver ultrasound. Differences between patients with and without NAFLD were compared. Data associated with stroke severity and progression after admission were collected. Results Non‐alcoholic fatty liver disease was found in 130 (42.5%) patients with acute BSI s; 58 (19.0%) had National Institutes of Health Stroke Scale scores 7 and 57 (18.6%) had progression after admission. Initial National Institutes of Health Stroke Scale scores, incidence of progression and stroke severity, and modified Rankin Scale scores at discharge were significantly higher in patients with NAFLD than in those without NAFLD . NAFLD was associated with stroke severity [Cox regression: hazard ratio ( HR ), 2.243; 95% confidence interval ( CI ), 1.254–4.013, P 0.01]. This risk remained statistically significant after controlling for age, gender, diabetes mellitus and C‐reactive protein ( HR , 2.327; 95% CI , 1.252–4.324, P 0.01). In addition, NAFLD was associated with progression ( HR , 2.155; 95% CI , 1.201–3.865, P 0.05) and remained significant after controlling for age, gender, diabetes mellitus, fibrinogen and C‐reactive protein ( HR , 2.378; 95% CI , 1.260–4.486, P 0.01). Conclusions These results suggest that NAFLD is a potential risk factor when evaluating the severity and progression of acute BSI s. This relationship is independent of classic risk factors and metabolic syndrome features.
机译：None

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号