Cell type-specific circular RNA expression in human glial cells

Curry-Hyde Ashton; Gray Lachlan G.; Chen Bei Jun; Ueberham Uwe; Arendt Thomas; Janitz Michael

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Cell type-specific circular RNA expression in human glial cells

机译：细胞类型特异性圆形RNA表达在人胶质细胞中

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摘要

The circular transcriptome of human glial cells is an area of neuroscience that has not been thoroughly elucidated. Circular RNAs (circRNAs) have the potential to facilitate the understanding of vast, complex and unknown mechanisms derived from the human transcriptome, including elements of the human brain that are not known and the evolution of the human brain, the complexities of which are not well understood. Moreover, the glial cells have been determined to contribute to human brain evolution. This study presents the first comprehensive analysis of the human brain glia circRNA transcriptome, that is, astrocytes, microglia and oligodendrocytes.

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来源
《Genomics》 |2020年第6期|共10页
作者
Curry-Hyde Ashton; Gray Lachlan G.; Chen Bei Jun; Ueberham Uwe; Arendt Thomas; Janitz Michael;
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作者单位

Univ New South Wales Sch Biotechnol &

Biomol Sci Sydney NSW 2052 Australia;

Univ New South Wales Sch Biotechnol &

Biomol Sci Sydney NSW 2052 Australia;

Nanyang Technol Univ Sch Biol Sci Singapore Singapore;

Univ Leipzig Paul Flechsig Inst Brain Res Leipzig Germany;

Univ Leipzig Paul Flechsig Inst Brain Res Leipzig Germany;

Univ New South Wales Sch Biotechnol &

Biomol Sci Sydney NSW 2052 Australia;

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原文格式 PDF
正文语种 eng
中图分类医学遗传学;
关键词
Circular RNAs; Circular transcriptome; Astrocytes; Microglia; Oligodendrocytes; RNA-seq;

机译：圆形RNA;圆形转录组;星形胶质细胞;小胶质细胞;少曲线肾细胞;RNA-SEQ;

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2. Comprehensive analysis of circular RNA expression profiles in cisplatin-resistant non-small cell lung cancer cell lines [J] . Lin Song, Zhilei Cui, Xuejun Guo 生物化学与生物物理学报：英文版 . 2020,第009期
3. Differential Circular RNA Expression in X-ray Radioresistant Non-small Cell Lung Carcinoma (NSCLC) Cells [J] . Jin Xiaodong, Liu Bingtao, Li Feifei, 中国科学院近代物理研究所和兰州重离子研究装置年报：英文版 . 2018,第001期
4. RNA sequencing to investigate the difference of circular RNA expression in peripheral blood mononuclear cells of patients with COPD [J] . Jun Zhang, Feng Zhan, Juan Sun, 海南医科大学学报(英文版) . 2021,第010期
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6. Circular RNA expression in human hematopoietic cells is widespread and cell-type specific [J] . Benoit P Nicolet, Sander Engels, Francesca Aglialoro, Nucleic acids research . 2018,第16期

机译：人类造血细胞中环状RNA表达广泛且细胞类型特异性
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机译：人造血细胞中的圆形RNA表达是普遍的和细胞类型
8. Expression of Long Non-Coding RNAs by Human Retinal Müller Glial Cells Infected with Clonal and Exotic Virulent Toxoplasma gondii [J] . Elise Rochet, Binoy Appukuttan, Yuefang Ma, Non-Coding RNA . 2019,第4期

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9. Transcriptome (RNA-seq) analysis of human salivary gland cells with exogenous expression of human pancreas beta cells transcription factors PDX1, MAFA, NGN3 [C] . Olga Brovkina, Yulia Kolesova, Mikhail Borisov, Conference on Cognitive Sciences, Genomics and Bioinformatics . 2020

机译：外源表达人胰腺β细胞转录因子PDX1，MAFA，NGN3的人唾液腺细胞的转录组（RNA-seq）分析
10. Regulation of the cell type-specific expression of the gene encoding glial fibrillary acidic protein. [D] . Sarkar, Srijata. 1990

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11. Circular RNA expression in human hematopoietic cells is widespread and cell-type specific [O] . Benoit P Nicolet, Sander Engels, Francesca Aglialoro, 2018

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13. Cell Type-Specific mRNA Amplification and Expression Profiling from Breast Tumor Sections. [R] . Albertson, D. G. 2001

机译：乳腺肿瘤切片的细胞类型特异性mRNa扩增和表达谱分析。

Cell type-specific circular RNA expression in human glial cells

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