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首页> 外文期刊>Annals of anatomy =: Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft >Distribution of calcitonin gene-related peptide (CGRP), substance P (SP) and galanin (GAL) immunoreactive nerve fibers in the seminal vesicle and prostate of the male sheep.
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Distribution of calcitonin gene-related peptide (CGRP), substance P (SP) and galanin (GAL) immunoreactive nerve fibers in the seminal vesicle and prostate of the male sheep.

机译：降钙素基因相关肽（CGRP），P物质（SP）和甘丙肽（GAL）免疫反应性神经纤维在雄性绵羊精囊和前列腺中的分布。

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摘要

Double immunohistochemistry was used to determine the occurrence and distribution pattern of nerve fibres immunoreactive to calcitonin gene-related peptide (CGRP), substance P (SP) and galanin (GAL) in seminal vesicles and prostate of the male sheep. Numerous CGRP- and SP-immunoreactive (IR) nerve fibres were found in the mucosal layer and smooth musculature of the seminal vesicles and prostate. In both glands nerve terminals immunoreactive to CGRP were more numerous than SP-IR ones. The majority of CGRP-IR nerve fibers showed colocalization of this peptide and SP. In both layers of the seminal vesicle and prostate, rare nerve terminals immunoreactive to GAL were also found. Immunoreactivity to SP was also found in all GAL-IR nerve fibers. The presence of numerous CGRP- and SP-IR nerve fibers in the seminal vesicle and prostate of the male sheep suggests that these neuropeptides may be involved in the sensory transmission and/or control of smooth muscle contractility. On the other hand, a relatively low number of GAL-IR nerve fibers of the seminal vesicle and prostate suggest that this peptide may act as an anti-nociceptive agent. It cannot be excluded that, in the seminal vesicle, GAL may also be involved in the control of the smooth muscle fiber activity. The possible role of CGRP, SP and GAL in the regulation of functions of the accessory sexual glands needs to be determined in further physiological studies.
机译：双重免疫组织化学用于确定与降钙素基因相关肽（CGRP），P物质（SP）和甘丙肽（GAL）免疫反应的神经纤维在雄性绵羊精囊和前列腺中的发生和分布方式。在精囊和前列腺的粘膜层和平滑肌组织中发现了许多CGRP和SP免疫反应（IR）神经纤维。在两个腺体中，对CGRP的免疫反应性都比SP-IR免疫反应性高。大部分CGRP-IR神经纤维均显示该肽和SP的共定位。在精囊和前列腺的两层中，还发现了对GAL具有免疫反应性的罕见神经末梢。在所有GAL-IR神经纤维中也发现了对SP的免疫反应性。在雄性绵羊的精囊和前列腺中存在大量的CGRP-和SP-IR神经纤维，这表明这些神经肽可能参与了感觉传递和/或平滑肌收缩力的控制。另一方面，精囊和前列腺的GAL-IR神经纤维数量相对较少，表明该肽可作为抗伤害感受剂。不能排除的是，在精囊中，GAL也可能参与平滑肌纤维活性的控制。 CGRP，SP和GAL在辅助性腺功能调节中的可能作用需要进一步的生理学研究来确定。

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