Exploration Disrupts Choice-Predictive Signals and Alters Dynamics in Prefrontal Cortex

Ebitz R. Becket; Albarran Eddy; Moore Tirin

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Exploration Disrupts Choice-Predictive Signals and Alters Dynamics in Prefrontal Cortex

机译：探索破坏了预测性信号并改变了前额叶皮质的动态

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In uncertain environments, decision-makers must balance two goals: they must "exploit'' rewarding options but also "explore'' in order to discover rewarding alternatives. Exploring and exploiting necessarily change how the brain responds to identical stimuli, but little is known about how these states, and transitions between them, change how the brain transforms sensory information into action. To address this question, we recorded neural activity in a prefrontal sensorimotor area while monkeys naturally switched between exploring and exploiting rewarding options. We found that exploration profoundly reduced spatially selective, choice-predictive activity in single neurons and delayed choice-predictive population dynamics. At the same time, reward learning was increased in brain and behavior. These results indicate that exploration is related to sudden disruptions in prefrontal sensorimotor control and rapid, reward-dependent reorganization of control dynamics. This may facilitate discovery through trial and error.

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《Neuron》 |2018年第2期|共21页
作者
Ebitz R. Becket; Albarran Eddy; Moore Tirin;
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Stanford Univ Sch Med Dept Neurobiol Stanford CA 94305 USA;

Stanford Univ Sch Med Dept Neurobiol Stanford CA 94305 USA;

Stanford Univ Sch Med Dept Neurobiol Stanford CA 94305 USA;

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原文格式 PDF
正文语种 eng
中图分类神经病学;
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6. Exploration Disrupts Choice-Predictive Signals and Alters Dynamics in Prefrontal Cortex [J] . Ebitz R. Becket, Albarran Eddy, Moore Tirin Neuron . 2018,第2期

机译：探索破坏了预测性信号并改变了前额叶皮质的动态
7. Exploration Disrupts Choice-Predictive Signals and Alters Dynamics in Prefrontal Cortex (vol 97, pg 450, 2018) [J] . Ebitz R. Becket, Albarran Eddy, Moore Tirin Neuron . 2018,第2期

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11. Exploration Disrupts Choice-predictive Signals and Alters Dynamics in Prefrontal Cortex [O] . R. Becket Ebitz, Eddy Albarran, Tirin Moore -1

机译：探索会破坏选择预测信号并改变前额叶皮层的动力学。
12. Exploration Disrupts Choice-Predictive Signals and Alters Dynamics in Prefrontal Cortex [O] . R. Becket Ebitz, Eddy Albarran, Tirin Moore 2018

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Exploration Disrupts Choice-Predictive Signals and Alters Dynamics in Prefrontal Cortex

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