Novel signatures associated with systemic lupus erythematosus clinical response to IFN-alpha/-omega inhibition

Seridi Loqmane; Cesaroni Matteo; Orillion Ashley; Schreiter Jessica; Chevrier Marc; Marciniak Stanley; Migone Thi-Sau; Stohl William; Chatham Walter Winn; Furie Richard Alan; Benson Jacqueline; Jordan Jarrat

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Novel signatures associated with systemic lupus erythematosus clinical response to IFN-alpha/-omega inhibition

机译：与系统性狼疮红斑狼疮相关的新签名对IFN-α/ omega抑制的临床反应

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《Lupus》 |2021年第5期|共12页
作者
Seridi Loqmane; Cesaroni Matteo; Orillion Ashley; Schreiter Jessica; Chevrier Marc; Marciniak Stanley; Migone Thi-Sau; Stohl William; Chatham Walter Winn; Furie Richard Alan; Benson Jacqueline; Jordan Jarrat;
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Janssen Res &

Dev LLC Spring House PA USA;

Janssen Res &

Dev LLC Spring House PA USA;

Janssen Res &

Dev LLC Spring House PA USA;

Janssen Res &

Dev LLC Spring House PA USA;

Janssen Res &

Dev LLC Spring House PA USA;

Janssen Res &

Dev LLC Spring House PA USA;

Univ Southern Calif Keck Sch Med Los Angeles CA 90007 USA;

UAB Med Birmingham AL USA;

Northwell Hlth Zucker Sch Med Hofstra Northwell Long Isl City NY USA;

Janssen Res &

Dev LLC San Francisco CA USA;

Janssen Res &

Dev LLC Cambridge MA 02142 USA;

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原文格式 PDF
正文语种 eng
中图分类免疫性疾病;
关键词
Systemic lupus erythematosus; biomarkers; monoclonal antibodies; type I interferon; precision medicine; transcription;

机译：Systemic Lupus红斑;生物标志物;单克隆抗体;I型干扰素;精确药;转录;

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1. Chinese Systemic Lupus Erythematosus Treatment and Research Group Registry IX: Clinical Features and Survival of Childhood?Onset Systemic Lupus Erythematosus in China [J] . Chan‑Yuan Wu, Meng‑Tao Li, Yan Zhao, 中华医学杂志（英文版） . 2017,第011期
2. Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/Ipr mouse model of systemic lupus erythematosus [J] . Samuel K Shimp III, Cristen B Chafin, Nicole L Regna, 细胞与分子免疫学：英文版 . 2012,第003期
3. Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/Ipr mouse model of systemic lupus erythematosus [J] . Samuel K Shimp Ⅲ, Cristen B Chafin, Nicole L Regna, 中国免疫学杂志（英文版） . 2012,第003期
4. Clinical Relevance of Autoantibodies against Interleukin-2 in Patients with Systemic Lupus Erythematosus [J] . Miao Shao, Xiao-Lin Sun, He Sun, 中华医学杂志（英文版） . 2018,第013期
5. Clinical applications of IFN-alpha blockade in systemic lupus erythematosus [J] . M Aringer, MK Crow, JS Smolen International journal of clinical rheumatology. . 2009,第6期

机译：IFN-α阻滞在系统性红斑狼疮中的临床应用
6. Association of systemic lupus erythematosus disease activity index?score with clinical and laboratory parameters in pediatric onset systemic lupus erythematosus [J] . Roshila Shamim, Sumaira Farman, Shabnam Batool, Pakistan journal of medical sciences. . 2020,第3期

机译：全身狼疮性疾病疾病活动指数的协会？与临床和实验室参数的分数在儿科发病系统狼疮红斑狼疮
7. The use of Systemic Lupus Erythematosus Disease Activity Index-2000 to define active disease and minimal clinically meaningfuln change based on data from a large cohort of systemic lupus erythematosus patients [J] . Caroline Gordon Rheumatology . 2011,第5期

机译：根据来自大量系统性红斑狼疮患者的数据，使用系统性红斑狼疮疾病活动指数-2000定义活动性疾病和最小的临床意义变化
8. Systemic lupus erythematosus: PKCA is an inhibition pathway for mTOR by the active ingredient of green tea [C] . H Mawarti, J Nugraha, D A Purwanto, International Seminar on Smart Molecule of Natural Resources . 2020

机译：Systemic Lupus红斑狼疮：PKCA是由绿茶活性成分的MTOR抑制途径
9. The regulation of IFN-alpha production in systemic and neuropsychiatric lupus erythematosus. [D] . Santer, Deanna M. 2010

机译：全身和神经精神性红斑狼疮中IFN-α产生的调节。
10. Omega-3 in SLE: a double-blind placebo-controlled randomized clinical trial of endothelial dysfunction and disease activity in systemic lupus erythematosus [O] . Kayode J. Bello, Hong Fang, Parastoo Fazeli, -1

机译：SLE中的Omega-3：双盲安慰剂对照的系统性红斑狼疮内皮功能障碍和疾病活动的随机临床试验
11. Omega-3 in SLE: a double-blind, placebo-controlled randomized clinical trial of endothelial dysfunction and disease activity in systemic lupus erythematosus [O] . Kayode J. Bello, Hong Fang, Parastoo Fazeli, 2013

机译：Omega-3在SLE：一种双盲，安慰剂控制的随机临床试验，内皮功能障碍和疾病活动中的狼疮红斑狼疮
12. Effects of Omega-3 Fatty Acids on Lipids and Glycemic Control in Type II Diabetes and the Metabolic Syndrome and on Inflammatory Bowel Disease, Rheumatoid Arthritis, Renal Disease, Systemic Lupus Erythematosus, and Osteoporosis Evidence Report/Technology [R] . Newberry, S. J., Gralnek, I., MacLean, C. H., 2004

机译：Omega-3脂肪酸对II型糖尿病和代谢综合征以及炎症性肠病，类风湿性关节炎，肾病，系统性红斑狼疮和骨质疏松症的血脂和血糖控制的影响证据报告/技术

Novel signatures associated with systemic lupus erythematosus clinical response to IFN-alpha/-omega inhibition

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