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Hostility now, depression later? Longitudinal associations among emotional risk factors for coronary artery disease.

机译:现在敌对,以后沮丧?冠状动脉疾病的情感危险因素之间的纵向关联。

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BACKGROUND/PURPOSE: Given that emotional risk factors for coronary artery disease (CAD) tend to cluster within individuals, surprisingly little is known about how these negative emotions might influence one another over time. We examined the longitudinal associations among measures of depressive symptoms and hostility/anger in a cohort of 296 healthy, older adults. METHODS: Participants completed the Beck Depression Inventory-II (BDI-II), Cook-Medley Hostility (Ho) scale, and Anger-In and Anger-Out subscales of the State-Trait Anger Expression Inventory at baseline and 6-year follow-up. We conducted a series of path analyses to evaluate the directionality of the depression-hostility/anger relationship. RESULTS: Baseline Ho scale was a predictor of 6-year increases in BDI-II (beta = 0.15, p = 0.004), Anger-In (beta = 0.14, p = 0.002), and Anger-Out (beta = 0.11, p = 0.01). In contrast, baseline BDI-II, Anger-In, and Anger-Out did not predict change in any of the emotional variables. Additional path analytic models revealed that the pattern of relationships was not altered after controlling for demographic, biomedical, and behavioral covariates; anxiety symptoms; social support; and subjective sleep quality. CONCLUSIONS: The present results suggest that the cognitive aspects of hostility/anger may precede and independently predict future increases in depressive symptoms but not vice versa. Our findings lead us to speculate that (a) hostility may exert part of its cardiotoxic influence by acting to precipitate and/or maintain symptoms of depression and that (b) the potency of depression interventions designed to improve cardiovascular outcomes might be enhanced by incorporating treatments addressing hostility.
机译:背景/目的:鉴于冠心病(CAD)的情感危险因素倾向于在个体中聚集,令人惊讶的是,这些负面情绪随着时间的推移如何相互影响知之甚少。我们在296名健康的老年人中研究了抑郁症状与敌意/愤怒之间的纵向相关性。方法:参与者在基线和六年随访期完成了贝克-抑郁量表-II(BDI-II),库克-梅德利敌对(Ho)量表以及州-特质愤怒表达量表的愤怒-投入和愤怒-退出子量表。向上。我们进行了一系列的路径分析,以评估抑郁-敌对/愤怒关系的方向性。结果:基线Ho量表是BDI-II(β= 0.15,p = 0.004),Anger-In(beta = 0.14,p = 0.002)和Anger-Out(beta = 0.11,p)6年增长的预测指标= 0.01)。相比之下,基线BDI-II,激怒和激怒并未预测任何情绪变量的变化。另外的路径分析模型表明,在控制人口统计学,生物医学和行为协变量后,关系的模式没有改变;焦虑症状社会支持;和主观睡眠质量。结论:目前的结果表明,敌意/愤怒的认知方面可能先于并独立地预测抑郁症状的未来增加,反之则不然。我们的发现使我们推测(a)敌对情绪可能通过发挥作用来加剧和/或维持抑郁症的症状,从而部分发挥其心脏毒性作用,并且(b)旨在改善心血管疾病结局的抑郁症干预措施的效力可以通过合并治疗得到增强解决敌对情绪。

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