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Determinants of Eimeria and Campylobocter infection dynamics in UK domestic sheep: the role of co-infection

机译:英国国内绵羊的艾美氏症和坎帕诺克治疗动力学的决定因素:共感染的作用

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摘要

Coccidiosis caused by Eimeria species is a well-recognized disease of livestock. Enteric Eimeria infections are common, but disease usually only manifests when infection intensity is abnormally high. Campylobacter species are important zoonotic enteric bacterial pathogens for which livestock are important reservoir hosts. The diversity and epidemiology of ovine Eimeria and Campylobacter infections on two farms in north-western England were explored through a 24-month survey of shedding in sheep feces. Most animals were infected with at least one of 10 different Eimeria species, among which E. bakuensis and E. ovinoidalis were most common. An animal's age and the season of sampling were associated with the probability and intensity of Eimeria infection. Season of sampling was also associated with the probability of Campylobacter infection. Interestingly, higher intensities of Eimeria infections were significantly more common in animals not co-infected with Campylobacter. We explored the determinants of E. bakuensis and E. ovinoidalis infections, observing that being infected with either significantly increased the likelihood of infection with the other. The prevalence of E. ovinoidalis infections was significantly lower in sheep infected with Campylobacter. Recognition that co-infectors shape the dynamics of parasite infection is relevant to the design of effective infection control programmes.
机译:球虫病由艾美耳球虫引起,是家畜常见的疾病。肠道艾美耳球虫感染很常见,但这种疾病通常只有在感染强度异常高时才会出现。弯曲杆菌是重要的人畜共患病肠道细菌病原体,家畜是重要的宿主。通过为期24个月的绵羊粪便脱落调查,探讨了英格兰西北部两个农场绵羊艾美耳球虫和弯曲杆菌感染的多样性和流行病学。大多数动物至少感染了10种不同艾美耳球虫中的一种,其中巴肯尼斯艾美耳球虫和卵形艾美耳球虫最为常见。动物的年龄和采样季节与艾美耳球虫感染的概率和强度有关。采样季节也与弯曲杆菌感染的可能性有关。有趣的是,较高强度的艾美耳球虫感染在未同时感染弯曲杆菌的动物中明显更常见。我们探讨了巴肯尼斯大肠杆菌和绵羊大肠杆菌感染的决定因素,观察到感染其中一种显著增加了感染另一种的可能性。在感染弯曲杆菌的绵羊中,绵羊E.ovinoidalis感染率显著降低。认识到共同感染者影响寄生虫感染的动态与设计有效的感染控制方案有关。

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