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首页> 外文期刊>Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies >Prevalence of Acute Neurologic Insults: A Case for Going Global
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Prevalence of Acute Neurologic Insults: A Case for Going Global

机译：急性神经系统侮辱的患病率：全球化的案例

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Among organ system dysfunction, neurologic dysfunction possibly has the most visible and far reaching impact on the child, the family and the society. Childhood neurodisability from acute insults can translate into years of lost human potential and a challenged life. To plan the strategies to reduce the burden of neurodisability secondary to acute neurologic insults, an estimate of the current burden of the insults collected from diverse settings across the world is needed. Such data can guide resource allocation, policy making, and further research. A previous retrospective cohort study from the United States reported on data from 273,900 admissions of children with neurologic diagnoses. The most common diagnoses were seizures (53.9%) and traumatic brain injury (17.3%). Several notable facts that emerged from this study were: children with neurologic diagnoses had nearly three times greater ICU use than other hospitalized children, accounted for nearly half of deaths, and had more than three times the mortality of other patients. Children with neurologic diagnoses also had a significantly longer median hospital length of stay than other children and greater median hospital costs. Although the data from above referred study are very large, it is representative of only one country. For generating broadly representative epidemiological data on acute neurologic insults, there is a need for global multiregion data. The Prevalence of Acute critical Neurological disease in children: a Global Epidemiological Assessment (PANGEA) study is a worthwhile attempt to address this need. In this international study, preliminary data from academic and resource-rich settings give initial estimates of nature of primary neurologic insults in children admitted to the PICUs. It is a well-executed example of an international collaborative epidemiological research study.
机译：在器官系统功能障碍中，神经系统功能障碍可能对儿童、家庭和社会产生最明显和最深远的影响。儿童期因急性侮辱而导致的神经残疾可能会导致多年的人类潜能丧失和生活受到挑战。为了制定减少急性神经损伤继发神经功能障碍负担的策略，需要对目前从世界各地不同环境中收集的损伤负担进行评估。这些数据可以指导资源分配、政策制定和进一步研究。美国先前的一项回顾性队列研究报告了273900例神经系统疾病患儿的入院数据。最常见的诊断是癫痫（53.9%）和创伤性脑损伤（17.3%）。从这项研究中得出的几个值得注意的事实是：患有神经系统疾病的儿童使用ICU的人数几乎是其他住院儿童的三倍，占死亡人数的近一半，死亡率是其他患者的三倍以上。患有神经系统疾病的儿童的平均住院时间明显长于其他儿童，平均住院费用也更高。尽管上述研究的数据非常大，但它只代表一个国家。为了生成具有广泛代表性的急性神经损伤流行病学数据，需要全球多区域数据。儿童急性重症神经系统疾病的患病率：一项全球流行病学评估（PANGEA）研究是解决这一需求的一次有价值的尝试。在这项国际研究中，来自学术和资源丰富的环境的初步数据初步估计了入住PICUs的儿童原发性神经损伤的性质。这是一项国际合作流行病学研究的良好范例。

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