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首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >Screening and linkage to care for hepatitis C among inpatients in Georgia's national hospital screening program
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Screening and linkage to care for hepatitis C among inpatients in Georgia's national hospital screening program

机译：筛选和联系在佐治亚国家医院筛查计划中的住院患者乙型肝炎的护理

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The country of Georgia initiated an ambitious national hepatitis C elimination program. To facilitate elimination, a national hospital hepatitis C screening program was launched in November 2016, offering all inpatients screening for HCV infection. This analysis assesses the effectiveness of the first year of the screening program to identify HCV-infected persons and link them to care. Data from Georgia's electronic Health Management Information System and ELIMINATION-C treatment database were analyzed for patients aged 18 years hospitalized from November 1, 2016 to October 31, 2017. We described patient characteristics and screening results and compared linked-to-care patients to those not linked to care, defined as having a test for viremia following an HCV antibody (anti-HCV) positive hospital screening. Of 291,975 adult inpatients, 252,848 (86.6%) were screened. Of them, 4.9% tested positive, with a high of 17.4% among males aged 40-49. Overall, 19.8% of antiHCV + patients were linked to care, which differed by sex (20.6% for males vs. 18.4% for females; p = .019), age (23.9% for age 50-59 years vs. 10.7% for age >= 70 years; p < .0001), and length of hospitalization (21.8% among patients hospitalized for 1 day vs. 16.1% for those hospitalized 11 + days; p = .023). Redundant screening is a challenge; 15.6% of patients were screened multiple times and 27.6% of anti-HCV + patients had a prior viremia test. This evaluation demonstrates that hospital-based screening programs can identify large numbers of anti-HCV + persons, supporting hepatitis C elimination. However, low linkage-to-care rates underscore the need for screening programs to be coupled with effective linkage strategies.
机译：格鲁吉亚发起了一项雄心勃勃的国家丙型肝炎消除计划。为了促进消除丙型肝炎，2016年11月启动了国家医院丙型肝炎筛查项目，为所有住院患者提供丙型肝炎病毒感染筛查。该分析评估了筛查项目第一年的有效性，以确定HCV感染者并将其与护理联系起来。针对2016年11月1日至2017年10月31日住院的18岁患者，分析了来自乔治亚州电子健康管理信息系统和消除-C治疗数据库的数据。我们描述了患者特征和筛查结果，并将与护理相关的患者和与护理无关的患者进行了比较，后者被定义为在HCV抗体（抗-HCV）阳性医院筛查后进行病毒血症检测。在291975名成人住院患者中，筛查了252848名（86.6%）。其中4.9%呈阳性，在40-49岁的男性中高达17.4%。总的来说，19.8%的抗-HCV+患者与护理有关，这与性别（男性为20.6%，女性为18.4%；p=0.019）、年龄（50-59岁为23.9%，年龄≥70岁为10.7%；p<0.0001）和住院时间（住院1天的患者为21.8%，住院11天以上的患者为16.1%；p=0.023）不同。重复筛查是一项挑战；15.6%的患者进行了多次筛查，27.6%的抗-HCV+患者之前进行过病毒血症检测。这项评估表明，基于医院的筛查项目可以识别大量抗-HCV+人群，支持消除丙型肝炎。然而，与护理的低关联率强调了筛查项目与有效关联策略相结合的必要性。

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