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首页> 外文期刊>Preventive Nutrition and Food Science >Protective Effects of Anthocyanin Extract from Purple Sweet Potato (Ipomoea batatas L.) on Blood MDA Levels, Liver and Renal Activity, and Blood Pressure of Hyperglycemic Rats
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Protective Effects of Anthocyanin Extract from Purple Sweet Potato (Ipomoea batatas L.) on Blood MDA Levels, Liver and Renal Activity, and Blood Pressure of Hyperglycemic Rats

机译：花青素提取物从紫色甘薯（Ipomoea Batatas L.）对血液MDA水平，肝癌和肾脏活性的保护作用及高血糖大鼠的血压

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摘要

There has been a dynamic progression in the study of purple sweet potatoes, particularly in regard to their antioxidant compounds, such as anthocyanins. Antioxidants can reduce oxidative stress due to hyperglycemia, therefore research into the protective effects of hyperglycemia is essential. This study was conducted to investigate the protective effects of anthocyanin extracts from purple sweet potatoes on blood malondialdehyde (MDA) levels, liver and renal activity, and blood pressure in hyperglycemic rats. Anthocyanin from purple sweet potato (APSP) was extracted with ethanol-citric acid 3% solvent. Twenty-four rats were split into four experimental groups: (i) healthy rats; (ii) hyperglycemic rats without anthocyanin treatment; (iii) hyperglycemic rats treated with APSP extract at a dose of 50 mg/kg; and (iv) hyperglycemic rats treated with APSP extract at a dose of 100 mg/kg. Rats received treatment for 35 days. The results showed that consumption of APSP significantly reduced levels of MDA inthe blood, and liver and renal systems. APSP could reduce the urea and creatinine levels, which are indicative of improved renal function. In addition, APSP could decrease serum glutamate oxalacetate transaminase and serum glutamate pyruvate transaminase levels, indicative of protective activity of the extract on liver, and decrease systolic blood pressure. Accordingly, it was concluded that APSP could be developed as a functional food for treatment of diabetes.
机译：紫色甘薯的研究取得了动态进展，尤其是在其抗氧化化合物方面，如花青素。抗氧化剂可以降低高血糖引起的氧化应激，因此研究高血糖的保护作用是必要的。本研究旨在研究紫色甘薯花青素提取物对高血糖大鼠血液丙二醛（MDA）水平、肝肾活动和血压的保护作用。以3%乙醇-柠檬酸为溶剂，从紫甘薯（APSP）中提取花青素。24只大鼠分为四个实验组：（i）健康大鼠；（ii）未经花青素治疗的高血糖大鼠；（iii）以50 mg/kg的剂量用APSP提取物治疗的高血糖大鼠；以及（iv）以100 mg/kg的剂量用APSP提取物治疗的高血糖大鼠。大鼠接受了35天的治疗。结果表明，摄入APSP可显著降低血液、肝脏和肾脏系统中的MDA水平。APSP可降低尿素和肌酐水平，这表明肾功能改善。此外，APSP可降低血清谷氨酸草酰乙酸转氨酶和血清谷氨酸丙酮酸转氨酶水平，表明提取物对肝脏具有保护作用，并降低收缩压。因此，可以得出结论，APSP可以被开发为治疗糖尿病的功能性食品。

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