Amygdalar volume and violent ideation in a sample at clinical high-risk for psychosis

Feng Xinyang; Provenzano Frank; Appelbaum Paul S.; Masucci Michael D.; Brucato Gary; Lieberman Jeffrey A.; Girgis Ragy R.

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Amygdalar volume and violent ideation in a sample at clinical high-risk for psychosis

机译：在精神病的临床高风险中的样品中Amygdalarar体积和剧烈思想

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We previously demonstrated that violent ideation predicts both violent acts and eventual progression to syndromal psychosis in individuals at clinical high-risk for psychosis (CHR). We performed amygdalar surface morphometry analysis on MRI scans from 70 CHR individuals, 21 of whom had violent ideation, 49 of whom did not. CHR individuals with violent ideation have abnormal and asymmetric amygdalar volumes. These data suggest some commonalities in the genesis of violence and aggression among clinical populations, as well as that there may be specific neurobiological links between violence and psychosis.

机译：我们之前已经证明，在临床精神病高危人群（CHR）中，暴力思维可以预测暴力行为和最终发展为综合征性精神病。我们对70名CHR患者的MRI扫描进行杏仁核表面形态计量分析，其中21人有暴力思维，49人没有。具有暴力思维的CHR个体杏仁核体积异常且不对称。这些数据表明，在临床人群中，暴力和攻击的成因有一些共同点，暴力和精神病之间可能存在特定的神经生物学联系。

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来源
《Psychiatry Research. Neuroimaging》 |2019年第1期|共3页
作者
Feng Xinyang; Provenzano Frank; Appelbaum Paul S.; Masucci Michael D.; Brucato Gary; Lieberman Jeffrey A.; Girgis Ragy R.;
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作者单位

Columbia Univ New York State Psychiat Inst Dept Psychiat 1051 Riverside Dr Unit 31 New York NY;

Columbia Univ New York State Psychiat Inst Dept Psychiat 1051 Riverside Dr Unit 31 New York NY;

Columbia Univ New York State Psychiat Inst Dept Psychiat 1051 Riverside Dr Unit 31 New York NY;

Columbia Univ New York State Psychiat Inst Dept Psychiat 1051 Riverside Dr Unit 31 New York NY;

Columbia Univ New York State Psychiat Inst Dept Psychiat 1051 Riverside Dr Unit 31 New York NY;

Columbia Univ New York State Psychiat Inst Dept Psychiat 1051 Riverside Dr Unit 31 New York NY;

Columbia Univ New York State Psychiat Inst Dept Psychiat 1051 Riverside Dr Unit 31 New York NY;

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原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学;
关键词
Violence; Ideation; Psychosis; Clinical high-risk; Amygdala; MRI;

机译：暴力;思想;精神病;临床高风险;asygdala;MRI;

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Amygdalar volume and violent ideation in a sample at clinical high-risk for psychosis

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