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首页> 外文期刊>The American journal of geriatric psychiatry: official journal of the American Association for Geriatric Psychiatry >Low Mood and Risk of Dementia: The Role of Marital Status and Living Situation
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Low Mood and Risk of Dementia: The Role of Marital Status and Living Situation

机译：情绪低的情绪和痴呆症风险：婚姻状况和生活的作用

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Objective: This study aims to explore whether low mood is related to an increased dementia risk in two cohorts of older adults of different generations, and whether marital status and living situation modify this association. Methods: Participants (>= 70 years), free from dementia and living at home, were identified from two population-based studies: the Kungsholmen Project (KP; n = 1,197) and the Swedish National Study on Aging and Care in Kungsholmen (SNAC-K; n = 1,402). Low mood was obtained by self-report (KP and SNAC-K) at baseline in 1987-89 (KP) and 2001-04 (SNAC-K). Incident dementia cases were ascertained over 9 years, using the same diagnostic procedures and comparable criteria for the two cohorts (DSM-III-R in KP and DSM-IV-TR in SNAC-K). Hazard ratios (HR) were derived from Cox proportional hazards models. Results: Those having low mood at baseline were at higher risk of dementia in both cohorts combined (HR: 1.2, 95% confidence interval (CI): 1.0-1.4) than those without low mood. However, an increased risk was detected only in those who did not have a partner (HR: 1.5, 95% CI: 1.2-1.9), or lived alone (HR: 1.5, 95% CI: 1.2-1.9), but not among those who had a partner or lived with someone (HR: 0.8, 95% CI: 0.5-1.2). Conclusion: Marital status and living situation have the potential to buffer the detrimental effects of low mood on dementia onset. Thus, specific attention from health care should target individuals having low mood and who do not have a partner or live alone.
机译：目的：本研究旨在探讨不同世代的两组老年人中，情绪低落是否与痴呆风险增加有关，以及婚姻状况和生活状况是否会改变这种关联。方法：从两项基于人群的研究中确定无痴呆症且住在家中的参与者（>=70岁）：Kungsholmen项目（KP；n=1197）和瑞典国家Kungsholmen老龄化和护理研究（SNAC-K；n=1402）。在1987-89年（KP）和2001-04年（SNAC-K）基线检查时，通过自我报告（KP和SNAC-K）获得低情绪。使用相同的诊断程序和两个队列的可比标准（KP中的DSM-III-R和SNAC-K中的DSM-IV-TR），在9年内确定了偶发性痴呆病例。风险比（HR）由Cox比例风险模型得出。结果：在两个队列中，基线时情绪低落的人患痴呆症的风险（HR:1.2，95%可信区间（CI）：1.0-1.4）均高于情绪低落的人。然而，只有那些没有伴侣（HR:1.5，95%可信区间：1.2-1.9）或独自生活（HR:1.5，95%可信区间：1.2-1.9）的人检测到风险增加，但在有伴侣或与某人一起生活的人中没有检测到风险增加（HR:0.8，95%可信区间：0.5-1.2）。结论：婚姻状况和生活状况有可能缓冲情绪低落对痴呆症发病的不利影响。因此，医疗保健部门应特别关注情绪低落、没有伴侣或独自生活的人。

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