Sexual Motivation and Sexual Reward in Male Rats are Attenuated by the Gonadotropin-Releasing Hormone Receptor Antagonist Degarelix

Hawley Wayne R.; Kapp Lauren E.; Dingle Clayton M.; Dufala Haley A.; Green Phoenix A.; Barnes Julia L.; Barwell Jessica L.

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Sexual Motivation and Sexual Reward in Male Rats are Attenuated by the Gonadotropin-Releasing Hormone Receptor Antagonist Degarelix

机译：雄性大鼠的性动机和性奖励由促性腺激素释放激素受体拮抗剂Degarix衰减

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Background: Preclinical studies that have examined the effects of androgen deprivation therapies (ADTs) on sexual outcomes have either relied on a surgical castration model of ADTs or have largely focused on consummatory sexual behaviors.

机译：背景：研究雄激素剥夺疗法（ADT）对性结局影响的临床前研究要么依赖于ADT的手术去势模型，要么主要集中于完善的性行为。

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来源
《The journal of sexual medicine》 |2021年第2期|共16页
作者
Hawley Wayne R.; Kapp Lauren E.; Dingle Clayton M.; Dufala Haley A.; Green Phoenix A.; Barnes Julia L.; Barwell Jessica L.;
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作者单位

Edinboro Univ Penn Dept Psychol 210 East Normal St Edinboro PA 16444 USA;

Edinboro Univ Penn Dept Psychol 210 East Normal St Edinboro PA 16444 USA;

Edinboro Univ Penn Dept Psychol 210 East Normal St Edinboro PA 16444 USA;

Edinboro Univ Penn Dept Psychol 210 East Normal St Edinboro PA 16444 USA;

Edinboro Univ Penn Dept Psychol 210 East Normal St Edinboro PA 16444 USA;

Edinboro Univ Penn Dept Psychol 210 East Normal St Edinboro PA 16444 USA;

Edinboro Univ Penn Dept Psychol 210 East Normal St Edinboro PA 16444 USA;

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原文格式 PDF
正文语种 eng
中图分类性卫生;
关键词
Degarelix; Sexual Motivation; Sexual Reward; Ejaculation; Anxiety; Sexual Stimulation;

机译：Degarelix;性动机;性奖励;射精;焦虑;性刺激;

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1. Effects of gonadotropin-releasing hormone antagonists on the expression of vascular endothelial growth factor and its receptors in a rat model of ovarian hyperstimulation syndrome [J] . TONG Xiao-mei, ZHANG Song-ying, SONG Tao, 中华医学杂志（英文版） . 2008,第023期
2. Plasma antioxidant capacity, sexual and thyroid hormones levels, sperm quantity and quality parameters in stressed male rats received nano-particle of selenium [J] . Rezaeian-Tabrizi M, Sadeghi AA 亚太生殖杂志（英文版） . 2017,第001期
3. Plasma antioxidant capacity, sexual and thyroid hormones levels, sperm quantity and quality parameters in stressed male rats received nano-particle of selenium [J] . Rezaeian-Tabrizi M, Sadeghi AA 亚太生殖杂志(英文版) . 2017,第001期
4. Administration of an oxytocin receptor antagonist attenuates sexual motivation in male rats [J] . D.S. Blitzer, T.E. Wells, W.R. Hawley Hormones and behavior . 2017,第期

机译：催产素受体拮抗剂的施用衰减雄性大鼠的性动力
5. Metabolite profiles of degarelix, a new gonadotropin-releasing hormone receptor antagonist, in rat, dog, and monkey. [J] . Sonesson A, Koechling W, Stalewski J, Drug Metabolism and Disposition: The Biological Fate of Chemicals . 2011,第10期

机译：地瑞瑞克（一种新的促性腺激素释放激素受体拮抗剂）在大鼠，狗和猴子中的代谢物谱。
6. Basolateral Amygdala Inactivation Reduces Sexual Motivation in Male Rats during Performance of a T-Maze Task with a Sexual Reward [J] . Marisela Hernández-González, Francisco Abelardo Robles Aguirre, Miguel ángel Guevara, Journal of Behavioral and Brain Science . 2014,第5期

机译：基底外侧杏仁核失活降低了雄性大鼠性行为的T迷宫任务的执行过程中的性动机。
7. Exposure to arsenite alters metabolism and sexual hormones in pregnant rats [C] . M.M. Bonaventura, N.S. Bourguignon, D. Rodriguez International Congress on Arsenic in the Environment . 2014

机译：暴露于亚砷酸盐改变孕鼠的新陈代谢和性激素
8. Effects of early isolation on the experiential, hormonal and neural regulation of sexual behavior in male Long-Evans rats [D] . Akbari, Emis 2009

机译：早期隔离对雄性Long-Evans大鼠性行为的体验，激素和神经调节的影响
9. Sexual Experience Changes Sex Hormones But Not Hypothalamic Steroid Hormone Receptor Expression in Young and Middle-aged Male Rats [O] . Di Wu, Andrea C. Gore -1

机译：性经验改变性激素但不是中年雄性大鼠的下丘脑类固醇激素受体表达
10. Effect of Postnatal Treatment with a Gonadotropin-Releasing Hormone Antagonist on Sexual Maturation of Male Rats1 [O] . Ilpo T. Huhtaniemi, Nava Nevo, Abraham Amsterdam, 1986

机译：产后治疗与促性腺激素释放激素拮抗剂对雄性大鼠性成熟的影响
11. Gonadotropin-Releasing Hormone Receptor Antagonists and Methods Relating Thereto. (PAT-APPL-11-166 358). [R] . Tucci, F., Conners, P. J., Zhu, Y. F., 2005

机译：促性腺激素释放激素受体拮抗剂及其相关方法。（paT-appL-11-166 358）。

Sexual Motivation and Sexual Reward in Male Rats are Attenuated by the Gonadotropin-Releasing Hormone Receptor Antagonist Degarelix

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