Resource Reallocation in Bacteria by Reengineering the Gene Expression Machinery

首页> 外文期刊>Trends in Microbiology >Resource Reallocation in Bacteria by Reengineering the Gene Expression Machinery

【24h】

Resource Reallocation in Bacteria by Reengineering the Gene Expression Machinery

机译：通过重新进入基因表达机械进行细菌的资源重新分配

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Bacteria have evolved complex regulatory networks to control the activity of transcription and translation, and thus the growth rate, over a range of environmental conditions. Reengineering RNA polymerase and ribosomes allows modifying naturally evolved regulatory networks and thereby profoundly reorganizing the manner in which bacteria allocate resources to different cellular functions. This opens new opportunities for our fundamental understanding of microbial physiology and for a variety of applications. Recent breakthroughs in genome engineering and the miniaturization and automation of culturing methods have offered new perspectives for the reengineering of the transcription and translation machinery in bacteria as well as the development of novel in vitro and in vivo gene expression systems. We review different examples from the unifying perspective of resource reallocation, and discuss the impact of these approaches for microbial systems biology and biotechnological applications.

机译：细菌进化出复杂的调节网络，在一系列环境条件下控制转录和翻译的活动，从而控制生长速度。重组RNA聚合酶和核糖体可以改变自然进化的调节网络，从而深刻重组细菌将资源分配给不同细胞功能的方式。这为我们对微生物生理学的基本理解和各种应用提供了新的机会。基因组工程的最新突破以及培养方法的小型化和自动化为细菌转录和翻译机制的重组以及新型体外和体内基因表达系统的开发提供了新的视角。我们从资源再分配的统一角度回顾了不同的例子，并讨论了这些方法对微生物系统生物学和生物技术应用的影响。

著录项

来源
《Trends in Microbiology》 |2017年第6期|共14页
作者

展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类微生物学;
关键词

相似文献

外文文献
中文文献
专利

1. DMTB： A comprehensive online resource of 16S rRNA genes, ecological metadata, oligonucleotides, and magnetic properties of magnetotactic bacteria [J] . LIN Wei, LI Bi, PAN YongXin 中国科学通报：英文版 . 2011,第006期
2. Expression of Mitochondrial Gene Fragments within the Tapetum Induce Male Sterility by Limiting the Biogenesis of the Respiratory Machinery in Transgenic Tobacco [J] . Felix Shaya, Svetlana Gaiduk, Ido Keren, 植物学报（英文版） . 2012,第002期
3. BacFlash signals acid-resistance gene expression in bacteria [J] . Di Wu, Xianhua Wang, Wenfeng Qi, 细胞研究（英文版） . 2021,第006期
4. Residual feed intake in beef cattle and its association with carcass traits, ruminal solid-fraction bacteria, and epithelium gene expression [J] . Ahmed A.Elolimy, Mohamed K.Abdelmegeid, Joshua C.McCann, 畜牧与生物技术杂志(英文版) . 2018,第004期
5. Development of a reversible regulatory system for gene expression in the cyanobacterium Synechocystis sp. PCC 6803 by quorum-sensing machinery from marine bacteria [J] . Junaid Muhammad, Inaba Yu, Otero Ana, Journal of Applied Phycology . 2021,第3期

机译：综合症综合症SP中基因表达的可逆调控系统的研制。来自海洋细菌的批量传感机械的PCC 6803
6. The value of an egg: Resource reallocation in ladybirds (Coleoptera: Coccinellidae) infected with male-killing bacteria [J] . Elnagdy S., Majerus M.E.N., Handley L.-J.L. Journal of evolutionary biology . 2011,第9a10期

机译：鸡蛋的价值：感染了雄性杀死细菌的瓢虫（鞘翅目：球虫）中的资源重新分配
7. Independent and dynamic reallocation of pitx gene expression during vertebrate evolution, with emphasis on fish pituitary development. [J] . Gene: An International Journal Focusing on Gene Cloning and Gene Structure and Function . 2008,第1a2期

机译：脊椎动物进化过程中pitx基因表达的独立和动态重分配，重点是鱼类垂体的发育。
8. ELECTROGENETIC ACTUATION OF GENE EXPRESSION IN BACTERIA: TOWARDS PROGRAMMABLE BIOLOGICAL FUNCTION BASED ON MOLECULAR SIGNALING [C] . William E. Bentley, Tanya Tschirhart, Eunkyong Kim, Biochemical and molecular engineering XX: the next generation of biochemical engineering: from nanoscale to industrial scale . 2017

机译：细菌中基因表达的电磁致动：基于分子信号的可编程生物学功能
9. Regulation of eukaryotic gene expression by mRNA cap binding complex and capping machinery. [D] . Lahudkar, Shweta. 2014

机译：通过mRNA帽结合复合物和加帽机制调节真核基因表达。
10. Metal Resistant Endophytic Bacteria Reduces Cadmium Nickel Toxicity and Enhances Expression of Metal Stress Related Genes with Improved Growth of Oryza Sativa via Regulating Its Antioxidant Machinery and Endogenous Hormones [O] . Rahmatullah Jan, Muhammad Aaqil Khan, Sajjad Asaf, 2019

机译：抗金属内生细菌通过调节其抗氧化机制和内源激素降低了镉镍的毒性并增强了稻的生长从而增强了金属胁迫相关基因的表达。
11. Metal Resistant Endophytic Bacteria Reduces Cadmium, Nickel Toxicity, and Enhances Expression of Metal Stress Related Genes with Improved Growth of Oryza Sativa, via Regulating Its Antioxidant Machinery and Endogenous Hormones [O] . Rahmatullah Jan, Muhammad Aaqil Khan, Sajjad Asaf, 2019

机译：耐金属内生细菌可通过调节其抗氧化机械和内源激素来降低镉，镍毒性，增强金属应力相关基因的表达，并提高金属应激相关基因的表达，并通过调节其抗氧化机械和内源激素
12. Specialized Genetic Recombination Systems in Bacteria: Their Involvement in Gene Expression and Evolution [R] . Kopecko, D. J. 1980

机译：细菌中的特殊基因重组系统：它们参与基因表达和进化

Resource Reallocation in Bacteria by Reengineering the Gene Expression Machinery

摘要

著录项

相似文献

相关主题

期刊订阅