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首页> 外文期刊>Annals of the Academy of Medicine, Singapore >Surgical Hand Antisepsis-A Pilot Study comparing Povidone Iodine Hand Scrub and Alcohol-based Chlorhexidine Gluconate Hand Rub.
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Surgical Hand Antisepsis-A Pilot Study comparing Povidone Iodine Hand Scrub and Alcohol-based Chlorhexidine Gluconate Hand Rub.

机译：外科手术手消毒-比较研究聚维酮碘手部磨砂膏和酒精基葡萄糖酸洗必泰手部磨砂膏的先导性研究。

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Introduction: The surgeon uses different methods of surgical hand antisepsis with the aim of reducing surgical site infections. To date, there are no local studies comparing the efficacy of iodine hand scrub against newer alcohol-based hand rubs with active ingredients. Our pilot study compares a traditional aqueous hand scrub using 7.5% Povidone iodine (PVP-I) against a hand rub using Avagard: 61% ethyl alcohol, 1% chlorhexidine gluconate. The outcome measure is the number of Colony Forming Units (CFU) cultured from 10-digit fingertip imprints on agar plates. Materials and Methods: Ten volunteers underwent 2 hand preparation protocols, with a 30-minute interval in between-Protocol A (3-minute of aqueous scrub using PVP-I) and Protocol B (3-minute of hand rub, until dry, using Avagard). In each protocol, fingertip imprints were obtained immediately after hand preparation (t0). The volunteers proceeded to don sterile gloves and performed specific tasks (suturing). At one hour, the gloves were removed and a second set of imprints was obtained (t1). Results: Four sets of fingertip imprints were obtained. All 10 participants complied with the supervised hand preparation procedures for each protocol. CFUs of initial fingertip imprints (t0): The median CFU counts for initial imprint was significantly higher in the PVP-I treatment (median = 6, Inter Quartile Range (IQR) = 33) compared to the Avagard treatment (median = 0, IQR = 0, P <0.001). CFUs of fingertip imprint at 1 hour (t1): The median CFU counts for second imprint (t1) was significantly higher in the PVP-I treatment (median = 0.5, IQR = 11) compared to the Avagard treatment (median = 0, IQR = 0, P = 0.009). Our results suggest that the Avagard was more efficacious than aqueous PVP-I scrub at reducing baseline colony counts and sustaining this antisepsis effect. Conclusion: Alcohol hand rub with an active compound, demonstrated superior efficacy in CFU reduction. Based on our results, and those pooled from other authors, we suggest that alcohol-based hand rubs could be included in the operating theatre as an alternative to traditional surgical scrub for surgical hand antisepsis.
机译：简介：外科医生采用不同的手术手防腐方法，以减少手术部位感染。迄今为止，尚无本地研究将碘洗手液与具有活性成分的新型酒精基洗手液的功效进行比较。我们的先导研究比较了使用7.5％聚维酮碘（PVP-I）的传统水洗手液和使用Avagard：61％乙醇，1％葡萄糖酸洗必泰的手洗液。结果度量是从琼脂平板上的10位指尖印记培养的菌落形成单位（CFU）的数量。材料和方法：十名志愿者接受了2次手准备方案，在协议A（使用PVP-1进行3分钟的水洗液）和方案B（3分钟的手洗，直至干燥）之间间隔30分钟Avagard）。在每种方案中，手准备后立即获得指尖印记（t0）。志愿者们继续戴无菌手套，并执行特定的任务（缝合）。一小时后，取下手套并获得第二组印记（t1）。结果：获得四组指尖印记。所有10名参与者均遵守每种规程的监督手准备程序。初始指尖印记的CFU（t0）：与Avagard处理（中位数= 0，IQR）相比，在PVP-I处理中，初始印记的CFU计数中位数显着更高（中位数= 6，四分位间距（IQR）= 33） = 0，P <0.001）。 1小时（t1）指尖印记的CFU：与Avagard处理（中位数= 0，IQR）相比，PVP-I治疗（中位数= 0.5，IQR = 11）中第二次印记的CFU计数中位数（t1）显着更高= 0，P = 0.009）。我们的结果表明，Avagard在降低基线菌落数和维持这种防腐效果方面比PVP-1水溶液更有效。结论：酒精与活性化合物的手揉搓，显示出降低CFU的优异功效。根据我们的研究结果以及其他作者的研究结果，我们建议在手术室中使用酒精基手部擦拭剂，以替代传统的手术手部防腐剂。

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