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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >An in vitro in vitro simulation model to assess the severity of edge loading and wear, due to variations in component positioning in hip joint replacements
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An in vitro in vitro simulation model to assess the severity of edge loading and wear, due to variations in component positioning in hip joint replacements

机译：一种体外体外模拟模型，以评估边缘装载和磨损的严重程度，因为髋关节置换中的元件定位变化

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Abstract The aim of this study was to develop a preclinical in vitro method to predict the occurrence and severity of edge loading condition associated with the dynamic separation of the centres of the head and cup (in the absence of impingement) for variations in surgical positioning of the cup. Specifically, this study investigated the effect of both the variations in the medial–lateral translational mismatch between the centres of the femoral head and acetabular cup and the variations in the cup inclination angles on the occurrence and magnitude of the dynamic separation, the severity of edge loading, and the wear rate of ceramic‐on‐ceramic hip replacement bearings in a multi‐station hip joint simulator during a walking gait cycle. An increased mismatch between the centres of rotation of the femoral head and acetabular cup resulted in an increased level of dynamic separation and an increase in the severity of edge loading condition which led to increased wear rate in ceramic‐on‐ceramic bearings. Additionally for a given translational mismatch, an increase in the cup inclination angle gave rise to increased dynamic separation, worst edge loading conditions, and increased wear. To reduce the occurrence and severity of edge loading, the relative positions (the mismatch) of the centres of rotation of the head and the cup should be considered alongside the rotational position of the acetabular cup. This study has considered the combination of mechanical and tribological factors for the first time in the medial–lateral axis only, involving one rotational angle (inclination) and one translational mismatch. ? 2017 The Authors Journal of Biomedical Materials Research Part B: Applied Biomaterials Published by Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 1897–1906, 2018.
机译：摘要本研究的目的是开发一种临床前体外方法，以预测与头部和杯中心的动态分离（在没有撞击的情况下）相关的边缘载荷条件的发生和严重性，从而改变杯的手术定位。具体而言，本研究调查了股骨头和髋臼杯中心之间的内侧-外侧平移错配的变化，以及髋臼杯倾角的变化对动态分离的发生和程度、边缘负荷的严重性和稳定性的影响，以及多站髋关节模拟器中陶瓷对陶瓷髋关节置换轴承在行走步态周期中的磨损率。股骨头和髋臼杯旋转中心之间的失配增加，导致动态分离程度增加，边缘载荷条件的严重程度增加，从而导致陶瓷-陶瓷轴承的磨损率增加。此外，对于给定的平移失配，杯倾角的增加会导致动态分离增加、边缘载荷条件最差以及磨损增加。为了减少边缘负荷的发生和严重程度，应将头部和髋臼杯旋转中心的相对位置（不匹配）与髋臼杯的旋转位置一起考虑。这项研究首次考虑了机械因素和摩擦学因素的组合，仅涉及一个旋转角度（倾角）和一个平移失配？2017年《生物医学材料研究作者杂志》B部分：威利期刊有限公司出版的应用生物材料J Biomed Mater Res B部分：Appl Biometer，106B:1897–19062018。

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