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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >An in vitro in vitro simulation model to assess the severity of edge loading and wear, due to variations in component positioning in hip joint replacements
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An in vitro in vitro simulation model to assess the severity of edge loading and wear, due to variations in component positioning in hip joint replacements

机译：一种体外体外模拟模型，以评估边缘装载和磨损的严重程度，因为髋关节置换中的元件定位变化

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Abstract The aim of this study was to develop a preclinical in vitro method to predict the occurrence and severity of edge loading condition associated with the dynamic separation of the centres of the head and cup (in the absence of impingement) for variations in surgical positioning of the cup. Specifically, this study investigated the effect of both the variations in the medial–lateral translational mismatch between the centres of the femoral head and acetabular cup and the variations in the cup inclination angles on the occurrence and magnitude of the dynamic separation, the severity of edge loading, and the wear rate of ceramic‐on‐ceramic hip replacement bearings in a multi‐station hip joint simulator during a walking gait cycle. An increased mismatch between the centres of rotation of the femoral head and acetabular cup resulted in an increased level of dynamic separation and an increase in the severity of edge loading condition which led to increased wear rate in ceramic‐on‐ceramic bearings. Additionally for a given translational mismatch, an increase in the cup inclination angle gave rise to increased dynamic separation, worst edge loading conditions, and increased wear. To reduce the occurrence and severity of edge loading, the relative positions (the mismatch) of the centres of rotation of the head and the cup should be considered alongside the rotational position of the acetabular cup. This study has considered the combination of mechanical and tribological factors for the first time in the medial–lateral axis only, involving one rotational angle (inclination) and one translational mismatch. ? 2017 The Authors Journal of Biomedical Materials Research Part B: Applied Biomaterials Published by Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 1897–1906, 2018.
机译：摘要该研究的目的是开发一种临床前体外方法，以预测与头部和杯中的中心的动态分离相关的边缘负载条件的发生和严重程度，以便在手术定位的外科定位变化中杯子。具体而言，本研究研究了股骨头和髋臼杯中心之间内侧横向平移失配的变化以及杯倾斜角度在动态分离的发生和幅度的变化，边缘的严重程度在步行步态周期中的多站髋关节模拟器中加载和陶瓷上髋关节置换轴承的磨损率。股骨头和髋臼杯的旋转中心之间的不匹配导致动态分离水平增加，并且边缘负载条件的严重程度的增加导致陶瓷轴承中的磨损率增加。另外，对于给定的平移失配，杯倾斜角的增加产生了增加动态分离，最差的边缘负载条件和增加的磨损。为了减少边缘加载的发生和严重程度，应将头部和杯子的旋转中心的相对位置（不匹配）沿着髋臼杯的旋转位置旁边。该研究仅考虑了机械和摩擦学因子的组合，仅在内侧轴线中首次，涉及一种旋转角度（倾斜）和一个平移错配。还2017年作者杂志生物医学材料研究第B部分：由Wiley期刊出版的应用生物材料，Inc。J生物密制Res Part B：Appl Biomater，106B：1897-1906,2018。

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