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首页> 外文期刊>Annals of nuclear medicine >Nuclear myocardial perfusion imaging with a cadmium-telluride semiconductor detector gamma camera in patients with acute myocardial infarction
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Nuclear myocardial perfusion imaging with a cadmium-telluride semiconductor detector gamma camera in patients with acute myocardial infarction

机译：镉-碲化物半导体探测器γ照相机对急性心肌梗死患者的核心肌灌注成像

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Objective: Since myocardial perfusion imaging (MPI) with conventional sodium iodine (NaI) device has low spatial resolution, there have been some cases in which small structures such as non-transmural myocardial infarction could not be properly detected. The purpose of this study was to evaluate potential usefulness of cadmium-telluride (CdTe) semiconductor detector-based high spatial resolution gamma cameras in detecting myocardial infarction sites, especially non-transmural infarction. Methods: A total of 38 patients (mean age ± SD: 64 ± 21 year) who were clinically diagnosed with acute myocardial infarction were included. Twenty-eight cases of them were with ST segment elevation myocardial infarction (STEMI) and 10 cases with non-ST segment elevation myocardial infarction (NSTEMI). In all patients, myocardial perfusion single photon emission computed tomography images were acquired with Infinia (NaI device) and R1-M (CdTe device), and the images were compared concerning the detectability of acute myocardial infarction sites. Results: The detection rates of the myocardial infarction site in cases with STEMI were 100 % both by NaI and CdTe images. In cases with NSTEMI, detection rate by NaI images was 50 %, while that of CdTe images was 100 % (p = 0.033). The summed rest score (SRS) value derived from CdTe images was significantly higher than that from NaI images in cases with STEMI [NaI images: 12 (7-18) versus CdTe images: 14 (9-20)] (p < 0.001). SRS derived from CdTe images was significantly higher than that derived from NaI images in cases with NSTEMI [NaI images: 2 (0-5) versus CdTe images: 6 (6-8)] (p = 0.006). Conclusions: These results indicate that MPI using CdTe-semiconductor device will provide a much more accurate assessment of acute myocardial infarction in comparison to current methods.
机译：目的：由于使用常规钠碘（NaI）装置进行的心肌灌注成像（MPI）的空间分辨率较低，因此在某些情况下无法正确检测到非透壁性心肌梗死等小结构。这项研究的目的是评估基于碲化镉（CdTe）半导体探测器的高空间分辨率伽马相机在检测心肌梗塞部位（尤其是非经壁梗塞）方面的潜在用途。方法：纳入临床诊断为急性心肌梗死的38例患者（平均年龄±SD：64±21岁）。其中28例ST段抬高型心肌梗死（STEMI）和10例非ST段抬高型心肌梗死（NSTEMI）。在所有患者中，均使用Infinia（NaI装置）和R1-M（CdTe装置）采集了心肌灌注单光子发射计算机断层扫描图像，并对图像进行了比较，探讨了急性心肌梗死部位的可检测性。结果：NaI和CdTe图像对STEMI患者的心肌梗死部位的检出率均为100％。在患有NSTEMI的病例中，NaI图像的检出率为50％，而CdTe图像的检出率为100％（p = 0.033）。在患有STEMI的病例中，来自CdTe图像的静止分数总和（SRS）值明显高于来自NaI图像的静止分数[NaI图像：12（7-18）vs CdTe图像：14（9-20）]（p <0.001） 。在NSTEMI的情况下，源自CdTe图像的SRS明显高于源自NaI图像的SRS [NaI图像：2（0-5）与CdTe图像：6（6-8）]（p = 0.006）。结论：这些结果表明，与目前的方法相比，使用CdTe半导体器件的MPI将提供对急性心肌梗死的更准确的评估。

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