Late onset hypersensitivity reaction to hyaluronic acid dermal fillers manifesting as cutaneous and visceral angioedema

Alawami Amal Z.; Tannous Zeina

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Late onset hypersensitivity reaction to hyaluronic acid dermal fillers manifesting as cutaneous and visceral angioedema

机译：晚期发作对透明质酸皮肤填料的反应，表现为皮肤和内脏血管内膜

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Introduction Hyaluronic acid fillers are gaining popularity all across the globe. Although this aesthetic treatment is considered relatively safe, or that most unwanted effects are related to technical faults of the injections or infections, hypersensitivity reactions are being reported in acute or delayed forms. We herein describe an unusual case of hypersensitivity reaction to hyaluronic acid dermal fillers of 12-month latency, manifesting as cutaneous and visceral angioedema, and refractory to steroids, antihistamines and omalizumab.

机译：简介透明质酸填充物在全球范围内越来越受欢迎。虽然这种美容治疗被认为是相对安全的，或者大多数不必要的影响都和注射或感染的技术故障有关，但过敏反应以急性或延迟的形式被报道。我们在此描述一例罕见的对透明质酸真皮填充物过敏反应，潜伏期为12个月，表现为皮肤和内脏血管水肿，对类固醇、抗组胺药和奥马利珠单抗不敏感。

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来源
《Journal of cosmetic dermatology》 |2021年第5期|共3页
作者
Alawami Amal Z.; Tannous Zeina;
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作者单位

Lebanese Amer Univ Div Dermatol Med Ctr Rizk Hosp Beirut Lebanon;

Lebanese Amer Univ Div Dermatol Med Ctr Rizk Hosp Beirut Lebanon;

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原文格式 PDF
正文语种 eng
中图分类皮肤病学;
关键词
angioedema; dermal filler; hyaluronic acid; hypersensitivity;

机译：血管内膜;皮肤填料;透明质酸;超敏反应;

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2. The interaction between hyaluronidase and hyaluronic acid gel fillers - a review of the literature and comparative analysis [J] . Michael K.Paap, Rona Z.Silkiss 整形与美容研究（英文版） . 2020,第007期
3. Late-Onset Adverse Reactions Related to Hyaluronic Acid Dermal Filler for Aesthetic Soft Tissue Augmentation [J] . Curi Marcos Martins, Cardoso Camila Lopes, Curra Claudia, The Journal of craniofacial surgery . 2015,第3期

机译：透明质酸皮肤填充剂引起的迟发不良反应，用于美学软组织增强
4. Delayed hypersensitivity reaction to hyaluronic acid dermal filler post-COVID-19 viral infection [J] . Shome Debraj, Doshi Komal, Vadera Sapna, Journal of cosmetic dermatology . 2021,第5期

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5. Hypersensitivity reaction to Hyaluronic Acid Dermal filler following novel Coronavirus infection - a case report [J] . Rowland-Warmann M. J. Journal of cosmetic dermatology . 2021,第5期

机译：新型冠状病毒感染后对透明质酸皮肤填料的过敏反应 - 一种情况报告
6. Injectable Hyaluronic Acid Gel Microspheres for Dermal Filler Applications [C] . Yun-Jeong Seong, Seol-Ha Jeong, Eun-Ho Song, Society for Biomaterials annual meeting and exposition . 2018

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7. Inhibition of lipid mediators in type I (immediate) hypersensitivity immune reactions by conjugated linoleic acid (CLA). [D] . Whigham, Leah Dawn. 2000

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8. Delayed hypersensitivity reaction to hyaluronic acid dermal filler following influenza-like illness [O] . Mohammed G Turkmani, Koenraad De Boulle, Wolfgang G Philipp-Dormston 2019

机译：流感样疾病后对透明质酸真皮填充剂的超敏反应延迟
9. Hypersensitivity reaction to Hyaluronic Acid Dermal filler following novel Coronavirus infection – a case report [O] . MJ Rowland‐Warmann 2021

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10. Sensitization Study by Dermal Administration in Guinea Pigs-Modified Buehler Design (Final Report) on C14-18 Alpha-olefin Epoxide, Reaction Products with Boric Acid. [R] . 2012

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Late onset hypersensitivity reaction to hyaluronic acid dermal fillers manifesting as cutaneous and visceral angioedema

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