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首页> 外文期刊>Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology >Anti-MOG antibodies associated demyelination following encephalomeningitis: Case report
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Anti-MOG antibodies associated demyelination following encephalomeningitis: Case report

机译：抗疗养抗体相关脱髓鞘后脑膜组织炎：病例报告

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摘要

Myelin oligodendrocyte glycoprotein (MOG) antibodies have been found in a broad range of demyelination diseases. In the present study, we reported three cases of patients with anti-MOG antibodies associated disorders (MOG-ADs) who initially presented as intracranial infection like encephalomeningitis with no evidence of demyelination injury, but were subsequently found the expression of MOG antibodies and other demyelination presentations. Our findings suggested that MOG-ADs can start as an intracranial infection like prodromal symptoms prior to the lesions of optic nerve, spinal cord, and white matter. Therefore, clinicians should be cautious of MOG-ADs in cases of encephalomeningitis even without demyelination injury.
机译：髓鞘少突胶质细胞糖蛋白（MOG）抗体已在广泛的脱髓鞘疾病中发现。在本研究中，我们报告了三例抗MOG抗体相关疾病（MOG-ADs）患者，他们最初表现为颅内感染，如脑脑膜炎，没有脱髓鞘损伤的证据，但随后发现了MOG抗体的表达和其他脱髓鞘表现。我们的研究结果表明，在视神经、脊髓和白质病变之前，MOG-ADs可先表现为颅内感染样前驱症状。因此，临床医生在没有脱髓鞘损伤的脑脑膜炎病例中应谨慎使用MOG-ADs。

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