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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Multicentric Experience with an Intermediate Aspiration Catheter for Distal M2 Ischemic Stroke
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Multicentric Experience with an Intermediate Aspiration Catheter for Distal M2 Ischemic Stroke

机译：用于远端M2缺血性卒中的中间抽吸导管的多中心体验

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摘要

Background: To assess technical and clinical outcomes of an intermediate bore aspiration catheter (AXS Catalyst 5; Stryker) as front-line therapy for M2-M3 acute occlusions. Methods: A multicentric, retrospective data collection of patients with symptomatic M2-M3 ischemic stroke, treated with direct aspiration first-pass technique was obtained. Time to recanalization, first attempt recanalization, and number of attempts were recorded. Successful recanalization was defined as a modified thrombolysis in cerebral infarction score >= 2b; incidence of procedure-related complications was recorded. National Institutes of Health Stroke Scale at discharge and modified Rankin Scale score at 90 days were evaluated by a dedicated neurologist. Results: A total of 44 acute occlusions of distal M2-M3 segment were treated with a direct aspiration first-pass technique using CAT 5 (mean age 68,4 years). Median NIHSS at baseline was 10. Overall modified thrombolysis in cerebral infarction score >= 2b was obtained in 90,9% of patients with mean time to recanalization of 49,7 minutes and a mean of 1.6 attempts. First-attempt recanalization with CAT 5 was obtained in 52,3% of patients with a mean time to recanalization of 29.2 min. A stent retriever with proximal aspiration was incorporated as a rescue device in 3 cases. No major complications was detected. The median National Institutes of Health Stroke Scale score at discharge was 4. At 90 days, a modified Rankin Scale score of 0-2 was achieved in 70,5% of patients. Conclusions: ADAPT technique with the intermediate aspiration catheter CAT 5 system achieves successful revascularization and functional independence for patients with acute ischemic stroke secondary to distal M2 occlusions.
机译：背景：评估中间孔抽吸导管（AXS Catalyst 5；Stryker）作为M2-M3急性闭塞症一线治疗的技术和临床效果。方法：收集症状性M2-M3缺血性中风患者的多中心、回顾性数据，采用直接抽吸首过技术进行治疗。记录再通时间、首次尝试再通和尝试次数。成功再通被定义为脑梗死改良溶栓评分>=2b；记录手术相关并发症的发生率。美国国立卫生研究院出院时的卒中量表和90天时的改良Rankin量表评分由专门的神经学家进行评估。结果：共有44例M2-M3远端急性闭塞采用CAT 5（平均年龄68,4岁）直接抽吸首过技术治疗。基线检查时NIHSS中位数为10。在90.9%的患者中，平均再通时间为49.7分钟，平均尝试次数为1.6次，总的脑梗死改良溶栓评分>=2b。52.3%的患者首次尝试使用CAT 5再通，平均再通时间为29.2分钟。3例患者使用带近端抽吸的支架回收器作为救援装置。未发现重大并发症。出院时，美国国立卫生研究院卒中量表得分中位数为4。90天时，70.5%的患者的改良Rankin量表得分为0-2。结论：对于继发于远端M2闭塞的急性缺血性卒中患者，采用中间抽吸导管CAT 5系统的ADAPT技术可实现成功的血运重建和功能独立性。

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