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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >COVID-19 Pandemic and Burden of Non-Communicable Diseases: An Ecological Study on Data of 185 Countries
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COVID-19 Pandemic and Burden of Non-Communicable Diseases: An Ecological Study on Data of 185 Countries

机译：Covid-19大流行和非传染性疾病的负担：185个国家数据的生态研究

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Background: The interaction between coronavirus disease 2019 (COVID-19) and non-communicable diseases may increase the global burden of disease. We assessed the association of COVID-19 with ageing and non-communicable diseases. Methods: We extracted data regarding non-communicable disease, particularly cardiovascular disease, deaths, disability-adjusted life years (DALYs), and healthy life expectancy (HALE) from the Global Burden of Disease Study (GBD) 2017. We obtained data of confirmed COVID-19 cases, deaths, and tests from the Our World in Data database as of May 28, 2020. Potential confounders of pandemic outcomes analyzed include institutional lockdown delay, hemispheric geographical location, and number of tourists. We compared all countries according to GBD classification and World Bank income level. We assessed the correlation between independent variables associated with COVID-19 caseload and mortality using Spearman's rank correlation and adjusted mixed model analysis. Findings: High-income had the highest, and the Southeast Asia, East Asia, and Oceania region had the least cases per million population (3050.60 vs. 63.86). Sub-saharan region has reported the lowest number of COVID-19 mortality (1.9). Median delay to lockdown initiation varied from one day following the first case in Latin America and Caribbean region, to 34 days in Southeast Asia, East Asia, and Oceania. Globally, non-communicable disease DALYs were correlated with COVID-19 cases (r = 0.32, p<0.001) and deaths (r = 0.37, p<0.001). HALE correlated with COVID-19 cases (r = 0.63, p<0.001) and deaths (r = 0.61, p<0.001). HALE was independently associated with COVID-19 case rate and the number of tourists was associated with COVID-19 mortality in the adjusted model. Interpretation: Preventive measures against COVID-19 should protect the public from the dual burden of communicable and non-communicable diseases, particularly in the elderly. In addition to active COVID-19 surveillance, policymakers should utilize this evidence as a guide for prevention and coordination of health services. This model is timely, as many countries have begun to reduce social isolation.
机译：背景：2019年新冠病毒病（COVID-19）与非传染性疾病之间的相互作用可能会增加全球疾病负担。我们评估2019冠状病毒疾病与老年和非传染性疾病的关联。方法：我们从2017年全球疾病负担研究（GBD）中提取了有关非传染性疾病，尤其是心血管疾病、死亡、残疾调整寿命（DALY）和健康预期寿命（HALE）的数据。2019冠状病毒疾病的死亡病例，我们在2020年5月28日的数据数据库中获得了来自世界的确认。分析的大流行结果的潜在混杂因素包括机构封锁延迟、半球地理位置和游客数量。我们根据GBD分类和世界银行收入水平对所有国家进行了比较。我们2019冠状病毒疾病的相关变量与Spearman等级相关和调整的混合模型分析评估了相关变量之间的相关性。研究结果：高收入人群的患病率最高，而东南亚、东亚和大洋洲地区的每百万人口患病率最低（3050.60比63.86）。撒哈拉以2019冠状病毒疾病死亡率最低（1.9）。从拉丁美洲和加勒比地区第一例病例发生后的一天到东南亚、东亚和大洋洲的34天，封锁启动的中位延迟时间各不相同。非传染性疾病DALYs 2019冠状病毒疾病与死亡相关（r＝0.32，P＜0.001），死亡与死亡相关（r＝0.37，P＜0.001）。与COVID2019冠状病毒疾病相关（r＝0.63，P＜0.001）和死亡（r＝0.61，P＜0.001）。与2019冠状病毒疾病2019冠状病毒疾病的死亡率相关，与调整后的模型中的COVID-19死亡率相关。解读：预防2019冠状病毒疾病的措施应保护公众免于传染病和非传染性疾病的双重负担，特别是老年人。除了积极的COVID-19监测，政策制定者应该利用这一证据作为预防和协调卫生服务的指南。这种模式是及时的，因为许多国家已经开始减少社会孤立。

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