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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Prognosis of Neurological Improvement in Inpatient Acute Ischemic Stroke Survivors: A Propensity Score Matching Analysis
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Prognosis of Neurological Improvement in Inpatient Acute Ischemic Stroke Survivors: A Propensity Score Matching Analysis

机译：住院性急性缺血性卒中幸存者的神经改善预后：倾向得分匹配分析

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Objectives: Stroke has become a national concern in China. Early prediction of stroke benefits patients and aids medical professionals in clinical decision making and rehabilitation plans to improve successful outcomes. To identify prediction factors influencing short-term outcomes in patients with acute ischemic stroke (AIS). Materials and Methods: This was a hospital-based prospective observational study. Recovery of neurological improvement was represented by a percent reduction in the National Institutes of Health Stroke Scale (NIHSS) at discharge. We performed propensity score matching (PSM) to balance the NIHSS at admission and compared NIHSS scores before and after matching with PSM criteria. Finally, we assessed the prognosis of neurological improvement and patient-related variables. Results: In the matched cohort, 92 pairs were matched by NIHSS admission after PSM. Modified Barthel Index, modified Rankin scale, NIHSS on admission, hypertension, sleep time, and Montreal Cognitive Assessment (MoCA) were statistically different between the two groups (P < 0.05) before matching. Multivariable analysis identified two factors independently associated with neurological improvement: diabetes (P = 0.030; adjusted odds ratio, 2.129; 95% confidence interval [CI] 1.078-4.026) and MoCA (P < 0.001; adjusted odds ratio, 5.385; 95% CI 2.278-12.730). Conclusion: Consistent with previous studies, diabetes affected the short-term outcomes of AIS, while cognitive impairment had a negative effect on long-term AIS prognosis.Diabetes and early cognitive impairment have adverse effects on short-term prognosis after AIS.
机译：目标：在中国，中风已成为全国关注的问题。在临床决策和康复计划中，中风的早期预测有助于患者和艾滋病医务人员提高成功率。确定影响急性缺血性卒中（AIS）患者短期预后的预测因素。材料和方法：这是一项基于医院的前瞻性观察研究。出院时，美国国立卫生研究院卒中量表（NIHSS）的神经功能改善恢复率下降了百分之十。我们进行倾向评分匹配（PSM）以平衡入院时的NIHSS，并将匹配前后的NIHSS评分与PSM标准进行比较。最后，我们评估了神经系统改善和患者相关变量的预后。结果：在配对队列中，92对患者在PSM后接受NIHSS治疗。匹配前，两组的改良Barthel指数、改良Rankin量表、入院时NIHSS、高血压、睡眠时间和蒙特利尔认知评估（MoCA）在统计学上存在差异（P<0.05）。多变量分析确定了与神经系统改善独立相关的两个因素：糖尿病（P=0.030；校正优势比，2.129；95%可信区间[CI]1.078-4.026）和MoCA（P<0.001；校正优势比，5.385；95%可信区间，2.278-12.730）。结论：与之前的研究一致，糖尿病影响AIS的短期预后，而认知障碍对AIS的长期预后有负面影响。糖尿病和早期认知障碍对AIS后的短期预后有不利影响。

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