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Brain Oscillatory Activity and Neurological Deficit in Hyper-acute Ischemic Stroke: Correlation of EEG Changes with NIHSS

机译:超急性缺血性脑卒中脑振荡活动和神经缺陷:脑电图脑电坡脑电图变化的相关性

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The accurate identification and prediction of cerebral infarct evolution and clinical outcome are of paramount importance in acute ischemic stroke management. Neuroimaging in acute stroke is mandatory to establish the feasibility of reperfusion therapy, but it is not practical to assess the continuous evolution of brain ischemia. EEG could be an applicable instrument to perform functional monitoring in the hyper-acute phase. EEG activity during ischemic stroke has been widely studied in sub-acute and post-acute phase of ischemic stroke. However, only few studies have focused on the early phase of brain ischemia. The aim of this study conducted at the stroke unit was to investigate stroke-related EEG changes during the earliest phase of ischemic stroke within 4.5 h from symptom onset and to correlate these data with neurological deficit in terms of NIHSS score. We studied 12 patients with ischemic stroke, who underwent EEG recordings within 4.5 h from symptom onset. The EEG signals acquisition was performed bedside without delaying reperfusion treatment, using @64 channels Wi-Fi Be Plus LTM amplifier and 19 channel 10-20 Ag/AgCl electrodes wireless prewired headset. The main finding of this study is a significant positive correlation between stroke-related EEG changes measured by DAR and DTABR parameters and the neurological deficit measured by NIHSS score, during the earliest phase of ischemic stroke. The results of this study highlight the importance of EEG as complementary tool in the assessment of stroke severity and its potential role in acute decision-making and monitoring.
机译:准确的脑梗死演化和临床结果的准确鉴定和预测对急性缺血性卒中管理至关重要。急性中风中的神经影像是必须建立再灌注治疗的可行性的强制性,但评估脑缺血的连续演变是不实际的。脑电图可以是适用于超急性期功能监测的适用仪器。在缺血性卒中期间的脑电图活动已被广泛研究缺血性卒中的亚急性和后急性期。然而,只有少数研究都集中在脑缺血的早期阶段。在卒中单元进行该研究的目的是在从症状发作期间,在4.5小时内缺血中风最早的缺血性卒中阶段进行脑卒中相关的脑电图变化,并在NIHSS评分方面将这些数据与神经缺陷相关联。我们研究了12名患有缺血性卒中患者,他从症状发作到4.5小时内完成脑电图录音。使用@ 64通道Wi-Fi加上LTM放大器和19通道10-20AG / AGCL电极无线预压耳耳机,在没有延迟再灌注处理的情况下进行床头段进行床头柜。本研究的主要发现是DAR和DTABR参数测量的中风相关的EEG变化与NIHSS得分测量的神经学缺陷在最早缺血性卒中期间测量的显着阳性相关性。本研究的结果突出了EEG作为补充工具在评估中风严重程度及其在急性决策和监测中的潜在作用中的互补工具的重要性。

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